Use of Phototherapy and Er-YAG Laser in the Management of Mandible Osteoradionecrosis: A Case Report.

IF 1.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Journal of lasers in medical sciences Pub Date : 2023-11-26 eCollection Date: 2023-01-01 DOI:10.34172/jlms.2023.58
Larissa Couto de Freitas, Elenice Lika Kawamoto, Ana Maria Aparecida Souza, Paulo Yataro Kawakami, Alyne Simões Gonçalves, Luciane Hiramatsu Azevedo
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Abstract

Introduction: Osteoradionecrosis (ORN) is a secondary complication from radiotherapy, which is difficult to manage and significantly reduces the life quality of the affected patients. Case Report: A 59-year-old female patient, diagnosed with infiltration by squamous cell carcinoma in the left cervical region, underwent adjuvant cervical-facial radiotherapy with a total dose of 66.6 Gy of radiation. Eight years after the diagnosis, the patient underwent multiple extractions and, subsequently, the installation of osseointegrated implants, evolving to extensive intraoral bone exposure associated with oral cutaneous fistula. The patient was initially exposed to photobiomodulation therapy (PBMT), with a low-power laser at wavelengths of 660 nm and 808 nm, and thereafter to antimicrobial photodynamic therapy (aPDT). After an improvement in the clinical condition and resolution of the oral cutaneous fistula, a surgical procedure with the Er: YAG laser was performed to remove the remaining necrotic bone. Once the ORN condition was completely treated, the patient's oral rehabilitation was implemented by the installation of an upper mucous-supported total prosthesis and a lower implant-supported prosthesis. Conclusion: The patient is in a clinical follow-up and has no signs of bone necrosis recurrence, suggesting that low and high-power laser treatment can be an effective therapeutic alternative to resolve this condition.

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使用光疗和 Er-YAG 激光治疗下颌骨骨坏死:病例报告。
简介骨坏死(ORN)是放疗的一种继发性并发症,难以控制,严重降低了患者的生活质量。病例报告:一名 59 岁的女性患者被诊断为左颈部鳞状细胞癌浸润,接受了总剂量为 66.6 Gy 的颈面部辅助放疗。确诊八年后,患者接受了多次拔牙手术,随后又安装了骨结合种植体,导致口内骨质广泛暴露,并伴有口腔皮肤瘘。患者最初接受了波长为 660 纳米和 808 纳米的低功率激光的光生物调节疗法(PBMT),之后又接受了抗菌光动力疗法(aPDT)。在临床症状改善、口腔皮肤瘘消退后,使用 Er: YAG 激光进行了手术,切除了剩余的坏死骨头。口腔瘘管病症得到彻底治疗后,为患者安装了上部粘液支持的全口义齿和下部种植支持的义齿,从而实现了口腔康复。结论:该患者目前正在接受临床随访,没有骨坏死复发的迹象,这表明低功率和高功率激光治疗是解决这一问题的有效治疗方法。
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来源期刊
Journal of lasers in medical sciences
Journal of lasers in medical sciences RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
3.00
自引率
13.30%
发文量
24
期刊介绍: The "Journal of Lasers in Medical Sciences " is a scientific quarterly publication of the Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences. This journal received a scientific and research rank from the national medical publication committee. This Journal accepts original papers, review articles, case reports, brief reports, case series, photo assays, letters to the editor, and commentaries in the field of laser, or light in any fields of medicine such as the following medical specialties: -Dermatology -General and Vascular Surgery -Oncology -Cardiology -Dentistry -Urology -Rehabilitation -Ophthalmology -Otorhinolaryngology -Gynecology & Obstetrics -Internal Medicine -Orthopedics -Neurosurgery -Radiology -Pain Medicine (Algology) -Basic Sciences (Stem cell, Cellular and Molecular application and physic)
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