[Lobular carcinoma of the breast with neuroendocrine differentiation. Study of a case].

Giornale italiano di oncologia Pub Date : 1989-04-01
A Risaliti, S Pizzolitto, M Menis, P F Tomada, A Cinque, C Melchior, M Rocco
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Abstract

A breast tumor with morphologic features of neuroendocrine differentiation and containing large amounts of estrogen receptor protein was associated with areas of typical infiltrating lobular carcinoma. The neuroendocrine areas were argyrophilic, NSE positive and ultrastructurally did not show dense granules. Results of flow cytometric analysis revealed aneuploid nuclear DNA.

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乳腺小叶癌伴神经内分泌分化。[案例研究]。
以神经内分泌分化为形态学特征,含有大量雌激素受体蛋白的乳腺肿瘤伴典型浸润性小叶癌。神经内分泌区呈嗜银性,NSE阳性,超微结构未见致密颗粒。流式细胞分析结果显示核DNA为非整倍体。
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