Preventive Effects of Prenatal Folic Acid on Postpartum Depression

IF 0.4 4区 医学 Q4 NUTRITION & DIETETICS Topics in Clinical Nutrition Pub Date : 2024-01-01 DOI:10.1097/TIN.0000000000000334
Xueqin Feng, Chunxia Wang, Fuling Wang, Xiaoyun Zhang, Hua Shu, Hui Chen, Liting Duan, Yuxi Wei, Jishui Wang, Dongmei Man, Fanyong Zhang
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Abstract

This study was conducted to assess the association of prenatal folic acid (PF) supplements on the onset of postpartum depression (PPD) in Chinese women. Of the 629 subjects, 540 were cases who took PF supplements and 89 were controls who did not take PF. Univariate analysis showed that maternal age and body mass index were the most significant risk factors for developing PPD. Threshold effect analysis showed that maternal age of more than 26 years was an independent determinant of PPD. Current findings with PF supplements are insufficient to attenuate the onset of PPD.
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产前叶酸对产后抑郁症的预防作用
本研究旨在评估产前补充叶酸(PF)与中国妇女产后抑郁症(PPD)发病的关系。在629名受试者中,540人为服用叶酸补充剂的病例,89人为未服用叶酸补充剂的对照组。单变量分析表明,产妇年龄和体重指数是产后抑郁症最重要的风险因素。阈值效应分析表明,产妇年龄超过 26 岁是 PPD 的独立决定因素。目前的研究结果表明,补充 PF 不足以减缓 PPD 的发生。
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来源期刊
Topics in Clinical Nutrition
Topics in Clinical Nutrition NUTRITION & DIETETICS-
CiteScore
0.90
自引率
20.00%
发文量
34
期刊介绍: ​​Topics in Clinical Nutrition (TICN) is a peer-reviewed, quarterly journal designed as a resource for the continuing education and clinical practice of dietitians and nutritionists. Each issue addresses topics of interest primarily to dietitians and nutritionists, students and interns in professional training programs and other health care personnel involved in the nutritional care of patients. Articles include translational research reports (work that applies new knowledge to practical effect), practice projects, evidence-based literature reviews, case studies and book reviews, and articles that highlight education theory and applied research which share the tools and techniques of nutrition and dietetics education.
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