Gabriel Francisco Pereira Aleixo , Holly Pederson , Nancy Dalpiaz , Jame Abraham
{"title":"Noninvasive prenatal testing detecting metastatic breast cancer: Case report and literature review","authors":"Gabriel Francisco Pereira Aleixo , Holly Pederson , Nancy Dalpiaz , Jame Abraham","doi":"10.1016/j.cpccr.2023.100277","DOIUrl":null,"url":null,"abstract":"<div><p>Noninvasive prenatal testing (NIPT) analyzes placental cell-free DNA in maternal blood for genetic abnormalities, especially in pregnant women of advanced maternal age. It is a high-sensitivity and specificity test used for screening fetal chromosome trisomy 13, 18, 21, sex chromosome aneuploidy, and rare fetal chromosome aneuploidy. Rarely there were cases in which it was used to diagnose maternal cancer. We will discuss a case of metastatic breast cancer diagnosed by NIPT and current knowledge on the use of this technology in diagnosing cancer during pregnancy.</p></div>","PeriodicalId":72741,"journal":{"name":"Current problems in cancer. Case reports","volume":"13 ","pages":"Article 100277"},"PeriodicalIF":0.2000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666621923000613/pdfft?md5=7b55634122888285d9962acb319ddb46&pid=1-s2.0-S2666621923000613-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current problems in cancer. Case reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666621923000613","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Noninvasive prenatal testing (NIPT) analyzes placental cell-free DNA in maternal blood for genetic abnormalities, especially in pregnant women of advanced maternal age. It is a high-sensitivity and specificity test used for screening fetal chromosome trisomy 13, 18, 21, sex chromosome aneuploidy, and rare fetal chromosome aneuploidy. Rarely there were cases in which it was used to diagnose maternal cancer. We will discuss a case of metastatic breast cancer diagnosed by NIPT and current knowledge on the use of this technology in diagnosing cancer during pregnancy.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
