Effect of alpha-lactalbumin isolated from camel milk on hyperlipidemia and hyperglycemia in experimental mice

Abstract

This study investigated the effect of α-lactalbumin which isolated from camel milk (a-Lac) at 200 and 400 mcg/day against metabolic disorders hyperlipidemia and hyperglycemia in cholesterol-induced lipidemia for mice. Monitor vital signs as weight of body, fasting glucose in blood level was observe after every week until 8 week (1st 4wk adaption and abnormaling 2nd, 4wk during treatment investigated), oral glucose tolerance test (OGTT) level and biochemical parameters were were measured after the second 4wk in blood and serum samples, like lipid profiles, insulin resistance, Liver enzymes including ALT, AST, and ALP. The results showed that camel α-La contributed effectively to maintaining vital indicators within healthy limits, and caused decreases in the level of hyperlipidemia and hyperglycemia. It gave activity to liver enzymes. The results were with a clear statistical difference, Recommend the use of camel whey proteins and α-La in particular due to its abundance in camel milk and its therapeutic properties.