Clinicoepidemiological Profile of Short Stature at A Tertiary Care Centre in Bangladesh

R. Biswas, Nahid Farzana, Sultana Nadira Rahman
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Abstract

Background: Short stature (SS) is a common pediatric problem, which can cause psychosocial disturbances both in parents and children. The goal of the evaluation of a child with SS is to identify the subset of children with pathologic causes so that appropriate timely intervention can be made. Objective: The aim of the study was to study the clinical, epidemiological, and etiological profile of SS at a tertiary hospital of Bangladesh. Methods: This was a cross-sectional study and was conducted in the department of pediatric endocrinology, over a period of 1 year (January 2021-December 2021). A total of 100 children aged 3-14 years, with height <-2SD below the mean height for age and sex were studied. Clinical history, examination, and laboratory evaluations were done to assess the cause of SS and the data were analyzed using appropriate statistical methods. Results: About 55% were female and 45% were male. The causes of SS were found to be familial SS (36%), constitutional growth delay of growth and puberty (12%), hypothyroidism (11%), growth hormone deficiency (8%), malnutrition (10%), chronic diseases (9%), genetic syndromes and skeletal problem (8%). Conclusion: The majority of short stature in children had normal variation of growth. Along with endocrine causes, chronic systemic illnesses and malnutrition still form a major bulk in the etiological profile of SS in Bangladesh. DS (Child) H J 2022; 38(2): 79-83
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孟加拉国三级医疗中心矮小身材的临床流行病学概况
背景:身材矮小(SS)是一种常见的儿科问题,可对父母和儿童造成心理社会困扰。对患有矮小症的儿童进行评估的目的是确定哪些儿童属于病理性矮小症,以便及时采取适当的干预措施。研究目的本研究旨在研究孟加拉国一家三级医院的 SS 临床、流行病学和病因概况。研究方法这是一项横断面研究,在儿科内分泌科进行,为期一年(2021 年 1 月至 2021 年 12 月)。共有 100 名 3-14 岁儿童接受了研究,他们的身高均低于同年龄和性别平均身高的 2SD 值。通过临床病史、检查和实验室评估来评估 SS 的病因,并采用适当的统计方法对数据进行分析。研究结果约 55% 为女性,45% 为男性。SS的病因包括家族性SS(36%)、生长和青春期发育迟缓(12%)、甲状腺功能减退(11%)、生长激素缺乏(8%)、营养不良(10%)、慢性疾病(9%)、遗传综合征和骨骼问题(8%)。结论大多数身材矮小的儿童发育正常。除内分泌原因外,慢性系统性疾病和营养不良仍是孟加拉国矮小症的主要病因。DS (Child) H J 2022; 38(2):79-83
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