The Modified Myocardial Index for Evaluation of Fetal Cardiac Function in Gestational Diabetes Mellitus

Yüksel Oğuz, Can Ozan Ulusoy, Recep Taha Agaoglu, Kadriye Yakut Yücel, Zehra Yilmaz
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Abstract

Objectives The modified myocardial performance index (Mod‐MPI) is a new technique that is used to assess myocardial function. Gestational Diabetes can affect myocardial function and may lead to change Mod –MPI value. We aimed to evaluate fetal cardiac function with Mod-MPI in pregnant with GDM and compare with healthy pregnant. Material and Methods Totally 60 pregnant; 30 with GDM and 30 without disease were included into this prospective case control study. Demographic characteristics of the study group were recorded. Mod-MPI and obstetric Doppler parameters were calculated for each fetus by an experienced perinatologist. The results of the two groups were compared. Results There was no difference in demographic characteristics terms of age, parity and BMI. The mean Mod-MPI value was found significantly higher in pregnant with GDM when compared with healthy pregnant. The obstetric Doppler parameters were found similar between groups. Conclusion The utility of the Mod‐MPI in GDM pregnant is unclear in literature. Future prospective studies with larger number of cases are needed to to evaluate the utility of the Mod‐MPI as a predictor of cardiac function in fetuses of GDM mothers.
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用于评估妊娠期糖尿病胎儿心脏功能的改良心肌指数
目的 改良心肌功能指数(Mod-MPI)是一种用于评估心肌功能的新技术。妊娠糖尿病会影响心肌功能,并可能导致 Mod-MPI 值发生变化。我们的目的是用 Mod-MPI 评估 GDM 孕妇的胎儿心功能,并与健康孕妇进行比较。 材料和方法 本前瞻性病例对照研究共纳入 60 名孕妇,其中 30 名患有 GDM,30 名未患病。记录研究组的人口统计学特征。由经验丰富的围产专家计算每个胎儿的 Mod-MPI 和产科多普勒参数。对两组结果进行比较。 结果 两组在年龄、胎次和体重指数等人口统计学特征方面没有差异。与健康孕妇相比,GDM 孕妇的 Mod-MPI 平均值明显偏高。各组间的产科多普勒参数相似。 结论 文献中对 GDM 孕妇使用 Mod-MPI 的效用尚不明确。未来需要对更多病例进行前瞻性研究,以评估 Mod-MPI 作为 GDM 母亲胎儿心脏功能预测指标的效用。
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