The History of Diabetes Mellitus

Rehan Haider, Asghar Mehdi
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Abstract

Diabetes mellitus, an incessant metabolic disorder caused by increased blood glucose levels, has a rich and complex history spanning paradise. The first famous reference to diabetes dates back to ancient Egypt, where the condition was defined in healing texts around 1500 BCE. However, it was not just before the 19th century that important progress had been made in understanding and directing diabetes. In 1889, two German physicians, Joseph von Mering, and Oskar Minkowski, fashioned an important finding by professing that the removal of organ meat in dogs caused diabetes-like manifestations. This led to the identification of organ meat as an insulin source. In 1921, a Canadian group led by Frederick Banting and Charles Best released insulin, a birth control method that is critical for regulating glucose levels. This finding was obvious at a critical juncture in diabetes administration, as insulin injections have become a lifesaving situation for things associated with type 1 diabetes
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糖尿病的历史
糖尿病是一种因血糖水平升高而导致的持续性代谢紊乱疾病,其丰富而复杂的历史跨越了天堂。关于糖尿病的最早记载可以追溯到公元前 1500 年左右的古埃及,在古埃及的医书中对糖尿病有明确的定义。然而,直到 19 世纪之前,人们才在了解和指导糖尿病方面取得了重要进展。1889 年,两位德国医生约瑟夫-冯-梅林(Joseph von Mering)和奥斯卡-明考斯基(Oskar Minkowski)发现了一个重要的发现,即狗吃内脏肉会导致类似糖尿病的表现。由此,内脏肉被认定为胰岛素来源。1921 年,弗雷德里克-班廷(Frederick Banting)和查尔斯-贝斯特(Charles Best)领导的加拿大小组发布了胰岛素,这是一种对调节葡萄糖水平至关重要的节育方法。这一发现在糖尿病治疗的关键时刻显而易见,因为注射胰岛素已成为 1 型糖尿病患者的救命稻草。
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