Case Report: Cryptococcal Meningitis as Stroke Mimic in ICL Patient

Sandeep Ghosh, Rohit Gupta, Megha Sharda, Sandip Bhattacharya, Ashok Kumar Sharma
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Abstract

Background : Cryptococcal infections are frequently encountered in immunocompromised patients including patients with idiopathic CD4 T cell lymphocytopenia (ICL). They are predisposed to severe Cryptococcal infections like Cryptococcal meningoencephalitis and few may present atypically as stroke mimic. Objective: To report a case of Cryptococcal meningoencephalitis in a patient with ICL who presented as stroke mimic. Methods and Material : We are reporting a case of an elderly gentleman who presented with symptoms and signs of acute stroke but upon evaluation he was diagnosed as Cryptococcal meningoencephalitis and ICL. Result: Cryptococcal meningoencephalitis may present as stroke mimic in immunocompromised patients having ICL. Conclusion : A high index of suspicion for Cryptococcal meningoencephalitis is warranted in immunocompromised patients with ICL who present with acute neurological signs and symptoms.
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病例报告:隐球菌性脑膜炎与 ICL 患者中风相似
背景:隐球菌感染经常发生在免疫力低下的患者中,包括特发性 CD4 T 细胞淋巴细胞减少症(ICL)患者。他们易患严重的隐球菌感染,如隐球菌脑膜脑炎,少数患者可能出现中风的非典型表现。目的:报告一例隐球菌脑膜脑炎病例。方法和材料:我们报告了一例老年男性患者,他出现急性中风的症状和体征,但经评估后被诊断为隐球菌脑膜脑炎和 ICL。结果:隐球菌性脑膜脑炎可作为中风的模拟病例出现在免疫功能低下的 ICL 患者中。结论:对于出现急性神经系统体征和症状的免疫功能低下的 ICL 患者,应高度怀疑隐球菌脑膜脑炎。
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