Adenoid Cystic Carcinoma of the Palate: Report Case

Berkaoui Mohamed, S. Mohamed, Barkiche Samir, Darfaoui Mouna, Elomrani Abdelhamid, Khouchani Mouna
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Abstract

Adenoid cystic carcinoma is a rare tumor, accounting for approximately 5–10% of all salivary gland neoplasms. It is a tumor which develops in 50 to 60% of cases on the minor salivary glands which are disseminated on the cheek; the lips; the palace; it is characterized by slow growth with a long-term natural evolution, quite aggressive locally, which has a tendency to local recurrence and even distant metastases (the first metastatic site of which is the lung). There are three subtypes that can exist in isolation or coexist together which are: solid; cribriform and tubular. The solid type has a poor prognosis unlike the cribriform type which has an intermediate prognosis and the tubular type which has the best prognosis. The treatment of choice remains surgical, often associated with adjuvant radiotherapy depending on the stage of progression (stage III and IV). It is almost not chemosensitive. It is a tenacious tumor and the survival rate at 05 years is 70%; after 10 years 50% and after 20 years 25%. We present a case of a 53-year-old patient; without particular pathological history, which presents an adenoid cystic carcinoma in its solid form locally advanced non-metastatic revealed by a budding mass of the hard and soft palate. Given the inoperability of the tumor; the patient was referred for Radiotherapy.
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腭腺样囊性癌:病例报告
腺样囊性癌是一种罕见肿瘤,约占所有唾液腺肿瘤的 5-10%。这种肿瘤有 50% 至 60% 的病例发生在小唾液腺上,散布在脸颊、嘴唇和宫颈;其特点是生长缓慢,长期自然演变,局部侵袭性强,有局部复发甚至远处转移的倾向(第一个转移部位是肺)。癌症有三种亚型,可以单独存在,也可以同时存在,它们是:实变型、楔形型和管状型。实体型预后较差,而楔形型预后居中,管状型预后最好。首选的治疗方法仍然是手术治疗,根据病情发展阶段(III 期和 IV 期),通常还需要辅助放疗。这种肿瘤对化疗几乎不敏感。它是一种顽固的肿瘤,05 年的生存率为 70%,10 年后为 50%,20 年后为 25%。我们介绍了一例 53 岁患者的病例,患者无特殊病史,表现为局部晚期非转移性固态腺样囊性癌,硬腭和软腭均有出芽肿块。鉴于肿瘤无法手术,患者被转诊接受放射治疗。
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