Misuse of Ozempic as a drug choice for weight loss, a potential threat

Uzma Aslam, Sarah Mehboob
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Abstract

The 387 million people around the globe are diagnosed with type 2 diabetes mellitus (T2DM). Previously used agents to treat T2DM posed adverse risks of hypoglycaemia and weight gain. Recently, Novo Nordisk, a pharmaceutical company, launched a new drug, Ozempic (Semaglutide), a glucagon-like peptide-1 receptor agonist (GLP-1 RA), which was approved by the US Food and Drug Administration on December 5, 2017. The numerous benefits of Ozempic makes it ideal for treatment of T2DM. Unfortunately, there is now an alarming shortage of Ozempic due to its misuse for weight loss.
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滥用 Ozempic 作为减肥药物的潜在威胁
全球有 3.87 亿人被诊断为 2 型糖尿病(T2DM)。以往用于治疗 T2DM 的药物存在低血糖和体重增加的不良风险。最近,诺和诺德制药公司推出了一种新药Ozempic(塞马鲁肽),这是一种胰高血糖素样肽-1受体激动剂(GLP-1 RA),于2017年12月5日获得美国食品药品管理局批准。Ozempic的众多优点使其成为治疗T2DM的理想药物。遗憾的是,由于被滥用于减肥,目前Ozempic的短缺情况令人担忧。
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