Nutritional Counseling Improves the Nutritional Status, Liver Function, and Serum Electrolytes of Patients with Liver Transplantation

Saba Tanveer, A. Alsubaie, Rezzan Khan, Hajra Ahmed, Mahpara Safdar, Zainab BiBi, Sadaf Yousaf, Bismillah Sehar, Iftikhar Alam, Aiman Hadayat, Falak Zeb
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Abstract

Nutrition counseling may assist liver transplant patients in controlling weight gain, addressing micronutrient deficiencies, and maintaining metabolic status. This study aimed to determine the effect of nutritional counseling on nutritional status, liver profile, and serum electrolytes of liver transplant patients. In this case-control study, 100 patients were recruited from Shifa International Hospital, Islamabad, who were potential liver transplant candidates. They were divided into two groups: a case group, who were given nutrition counseling (n = 50), and a control group, who were not provided nutrition counseling (n = 50). Data was collected about patients' socio-economic status, medical history, anthropometric, biochemical and dietary profiles. Independent t-tests, chi-square tests for qualitative frequency distribution, and paired t-tests were used. At baseline, the weight and BMI of the case and control were comparable, but there was a non-significant difference. Nutrition counseling was effective in improving biochemical variables (potassium at preoperative, sodium and albumin during illness; p-value < 0.05), Liver function (ALT at preoperative and postoperative, AKT at preoperative, during sickness and postoperative; p-value < 0.05) and macronutrient profile (fat intake during illness and protein intake during postoperative stage; p-value < 0.05) in case group as compared to control. Effective nutrition counseling improves liver transplant patients' nutritional status, liver function, and serum electrolytes.
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营养咨询可改善肝移植患者的营养状况、肝功能和血清电解质
营养咨询可帮助肝移植患者控制体重增加、解决微量营养素缺乏问题并维持新陈代谢状态。本研究旨在确定营养咨询对肝移植患者的营养状况、肝功能和血清电解质的影响。在这项病例对照研究中,研究人员从伊斯兰堡希法国际医院招募了 100 名可能接受肝移植的患者。他们被分为两组:接受营养咨询的病例组(50 人)和未接受营养咨询的对照组(50 人)。研究人员收集了患者的社会经济状况、病史、人体测量、生化和饮食概况等数据。采用独立 t 检验、定性频率分布的卡方检验和配对 t 检验。基线时,病例和对照组的体重和体重指数相当,但差异不显著。与对照组相比,营养咨询能有效改善病例组的生化变量(术前的钾、患病期间的钠和白蛋白;P值<0.05)、肝功能(术前和术后的ALT、术前、患病期间和术后的AKT;P值<0.05)和宏量营养素谱(患病期间的脂肪摄入量和术后阶段的蛋白质摄入量;P值<0.05)。有效的营养咨询可改善肝移植患者的营养状况、肝功能和血清电解质。
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