{"title":"Quarter-Century Experience in Cryopreservation of Human Oocytes by Vitrifi cation. What Has Been Achieved and What is Next?","authors":"T. Yurchuk, M. Petrushko","doi":"10.15407/cryo33.03.177","DOIUrl":null,"url":null,"abstract":"Cryopreservation of human oocytes by the vitrification has become a part of the daily practice of assisted reproductive technologies to fight an infertility and to preserve the woman's reproductive potential. This literature review covers the results of the studies performed by various scientific schools during 25 years; historical prerequisites for the development of cryopreservation of human oocytes by vitrification; medical and social indices to apply this method, features and complications arising during vitrification of human oocytes. Special attention has been paid to the issues regarding the genetic safety of the method mentioned in respect of the health of future descendants. The paper presents the insight on unsolved tasks in vitrification of oocytes and that of identified ways to overcome the challenges.","PeriodicalId":53457,"journal":{"name":"Problems of Cryobiology and Cryomedicine","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Problems of Cryobiology and Cryomedicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15407/cryo33.03.177","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Cryopreservation of human oocytes by the vitrification has become a part of the daily practice of assisted reproductive technologies to fight an infertility and to preserve the woman's reproductive potential. This literature review covers the results of the studies performed by various scientific schools during 25 years; historical prerequisites for the development of cryopreservation of human oocytes by vitrification; medical and social indices to apply this method, features and complications arising during vitrification of human oocytes. Special attention has been paid to the issues regarding the genetic safety of the method mentioned in respect of the health of future descendants. The paper presents the insight on unsolved tasks in vitrification of oocytes and that of identified ways to overcome the challenges.
期刊介绍:
The Journal publishes the reviews and original papers on cryobiological and cryomedical research, in particular the elucidation of mechanisms of injuries occurring in biological objects and caused by the influence of low and ultra low temperatures; natural resistance of biologicals to cold and their recovery post effect; the development of effective methods of cryoprotection and technology of storage of biological resources under hypothermic and ultra low temperatures, application of hypothermia, cryotherapy and cryopreserved biologicals for treating various pathologies; cell and tissue based therapies and other issues of low-temperature biology and medicine, as well as development of devices and equipment for low temperature biology and medicine. The journal covers all topics related to low temperature biology, medicine and engineering. These include but are not limited to: low temperature storage of biologicals (human, animal or plant cells, tissues, and organs), including preparation for storage, thawing/warming, cell and tissue culturing etc. response of biologicals to low temperature; cold adaptation of animals and plants; utilisation of low temperature in medicine; experimental and clinical transplantation, cell and tissue based therapies; developing of cryobiological and cryomedical devices; organisation and functioning of low temperature banks etc.