Analisis Hasil Deteksi SARS-COV2 Menggunakan Rapid Tes Antigen di Laboratorium Mikrobiologi Klinik RSUD dr. Doris Sylvanus Palangkaraya

Silvani Permatasari, Florence Felicia, Ni Putu W.S.W, M. Misbah, Arnino A, Dede Z. A, Yanuardi Ikhsan, Rini Fitri R, C. Chandra, Febrianto E. P
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Abstract

The antigen rapid diagnostic test is used for screening COVID-19 patients and is easy to do anywhere and saves time. The sensitivity of various brands of rapid antigen test kits can vary, so medical personnel need to pay close attention to them. Testing for the SARS-CoV2 antigen kit needs to be done diagnostically. This study aims to determine the specificity, sensitivity, and accuracy of the Haelgen antigen rapid test through diagnostic tests. The study design was cross-sectional, with a total sample of 60 people who took swabs from the nasopharynx and oropharynx. The sample is placed in the viral transport medium (VTM). Samples were examined by RT-PCR and, at the same time, examined using an antigen rapid test. The results of the analysis were carried out by calculating the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of the SARS-Cov2 antigen test compared to standard RT-PCR using a diagnostic test formula. The most common characteristics of COVID-19 patients were female and 20–29 years old (28.3%). The results of the Haelgen rapid antigen diagnostic test showed a sensitivity of 92.31%, a specificity of 100%, a positive predictive value of 100%, a negative predictive value of 87.5%, and an accuracy of 95%. The sensitivity, specificity, and accuracy of the Haelgen rapid antigen are suitable for testing for COVID-19.
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巴颜喀拉雅皇家医学院临床微生物实验室使用快速抗原检测法对 SARS-COV2 检测结果的分析
抗原快速诊断检测用于筛查 COVID-19 患者,在任何地方都能轻松完成,而且节省时间。各种品牌的抗原快速检测试剂盒的灵敏度可能不同,因此医务人员需要密切关注。对 SARS-CoV2 抗原试剂盒的检测需要进行诊断。本研究旨在通过诊断测试确定海尔根抗原快速检测试剂盒的特异性、灵敏度和准确性。研究设计为横断面,共抽取了 60 人的鼻咽和口咽拭子样本。样本置于病毒运输培养基(VTM)中。通过 RT-PCR 对样本进行检测,同时使用抗原快速检测法对样本进行检测。分析结果是通过使用诊断测试公式计算 SARS-Cov2 抗原测试与标准 RT-PCR 相比的灵敏度、特异性、阳性预测值(PPV)、阴性预测值(NPV)和准确性。COVID-19 患者最常见的特征是女性和 20-29 岁(28.3%)。海尔根快速抗原诊断测试结果显示,灵敏度为 92.31%,特异性为 100%,阳性预测值为 100%,阴性预测值为 87.5%,准确率为 95%。海尔根快速抗原的灵敏度、特异性和准确性均适合用于检测 COVID-19。
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