CLINICAL AND PSYCHIATRIC CHANGES IN EPILEPTIC PATIENTS WITH COVID-19 INFECTION

J.P. Isayev, H.H. Mammadova, N. Taghıyeva
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Abstract

The article provides information about clinical and mental changes in epileptic patients who have experienced COVID-19 infection. The frequency of these symptoms, their clinical characteristics and the dependence of their manifestation on the infection of COVID-19 were investigated. Various scales or questionnaires were used in the research. Observations have shown that epileptic seizures on the NHS-3 scale occur more frequently and tend to increase in severity in epileptic patients who have had an infection with COVID-19. When assessing the mental sphere of their patients (with the MMSE and HADS scales), it was found that cases of mental spectrum disorders prevail in epileptic patients who have experienced COVID-19. The presence of mild depression (BDI scale) and severe asthenia (MFI scale) were also more marked in this group. Analysis of the results showed that epileptic patients who had experienced a COVID-19 infection were more likely to have impaired cognitive function. Sleep disturbances were assessed using the MOS-SS scale, and it was found that epileptic patients with coronovirus infection were more likely to have moderate sleep disturbances than those without COVID-19. During the correlation analysis, it was determined that there is a direct positive relationship between the severity and frequency of epileptic seizures with the infection of COVID-19. All this shows the negative effect of the infection of COVID-19 on the course of epilepsy.
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感染 covid-19 的癫痫患者的临床和精神变化
文章介绍了感染 COVID-19 的癫痫患者的临床和精神变化。文章调查了这些症状的出现频率、临床特征及其表现与 COVID-19 感染的相关性。研究中使用了各种量表或问卷。观察结果表明,在感染 COVID-19 的癫痫患者中,NHS-3 量表中的癫痫发作频率更高,严重程度也有增加的趋势。在对患者的精神状况进行评估时(采用 MMSE 和 HADS 量表),研究发现,感染 COVID-19 的癫痫患者普遍存在精神障碍。在这一群体中,轻度抑郁(BDI 量表)和重度气喘(MFI 量表)也更为明显。分析结果表明,感染过 COVID-19 的癫痫患者更有可能出现认知功能受损。使用 MOS-SS 量表对睡眠障碍进行评估,结果发现,与未感染 COVID-19 的癫痫患者相比,感染冠状病毒的癫痫患者更有可能出现中度睡眠障碍。在进行相关性分析时,确定癫痫发作的严重程度和频率与感染 COVID-19 有直接的正相关关系。这一切都表明,感染 COVID-19 对癫痫的病程有负面影响。
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