{"title":"Screening Preeclampsia and the Role of Low Dose Aspirin for the Prevention of Preeclampsia","authors":"Wayan Artana Putra","doi":"10.3889/oamjms.2023.11214","DOIUrl":null,"url":null,"abstract":"Preeclampsia is one of the leading causes of maternal morbidity and can affect fetal conditions such as inhibition of intrauterine growth, premature labor, placental abruption, fetal distress, and, worst of all, intrauterine fetal death. In contrast to the decreasing incidence of pregnancies with infection, preeclampsia did not decrease significantly during the past two decades. Prevention of preeclampsia is an effort that is currently being intensively carried out to reduce morbidity and mortality of pregnant women. Prophylactic administration of low-dose aspirin (81 mg/day) is recommended in women with a high risk of preeclampsia. It should be started between 12 weeks of gestation to 18 weeks (optimal before 16 weeks). Aspirin has been shown to be safe for the mother and the fetus during pregnancy. Treatment with aspirin also did not increase the risk of developing congenital malformations and had no adverse effect on fetal development or bleeding complications during the neonatal period.","PeriodicalId":19562,"journal":{"name":"Open Access Macedonian Journal of Medical Sciences","volume":"60 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Access Macedonian Journal of Medical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3889/oamjms.2023.11214","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Preeclampsia is one of the leading causes of maternal morbidity and can affect fetal conditions such as inhibition of intrauterine growth, premature labor, placental abruption, fetal distress, and, worst of all, intrauterine fetal death. In contrast to the decreasing incidence of pregnancies with infection, preeclampsia did not decrease significantly during the past two decades. Prevention of preeclampsia is an effort that is currently being intensively carried out to reduce morbidity and mortality of pregnant women. Prophylactic administration of low-dose aspirin (81 mg/day) is recommended in women with a high risk of preeclampsia. It should be started between 12 weeks of gestation to 18 weeks (optimal before 16 weeks). Aspirin has been shown to be safe for the mother and the fetus during pregnancy. Treatment with aspirin also did not increase the risk of developing congenital malformations and had no adverse effect on fetal development or bleeding complications during the neonatal period.
期刊介绍：
Open Access Macedonian Journal of Medical Sciences (OAMJMS) [formerly known as Macedonian Journal of Medical Sciences] is a top-tier open access medical science journal published by the ID Design 2012/DOOEL Skopje, Rajko Zhinzifov No 48, 1000 Skopje, Republic of Macedonia. OAMJMS is an international, modern, general medical journal covering all areas in the medical sciences, from basic studies to large clinical trials and cost-effectiveness analyses. We publish mostly human studies that substantially enhance our understanding of disease epidemiology, etiology, and physiology; the development of prognostic and diagnostic technologies; trials that test the efficacy of specific interventions and those that compare different treatments; and systematic reviews. We aim to promote translation of basic research into clinical investigation, and of clinical evidence into practice. We publish occasional studies in animal models when they report outstanding research findings that are highly clinically relevant. Our audience is the international medical community as well as educators, policy makers, patient advocacy groups, and interested members of the public around the world. OAMJMS is published quarterly online version. The Open Access Macedonian Journal of Medical Sciences (OAMJMS) publishes Medical Informatics, Basic Science, Clinical Science, Case Report, Brief Communication, Public Health, Public Policy, and Review Article from all fields of medicine and related fields. This journal also publishes, continuously or occasionally, the bibliographies of the members of the Society, medical history, medical publications, thesis abstracts, book reviews, reports on meetings, information on future meetings, important events and dates, and various headings which contribute to the development of the corresponding scientific field.
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