Giant exophytic gastrointestinal stromal tumor (GIST) causing gastric outlet obstruction: case report and review of literature.

IF 1.2 4区医学 Q4 DEVELOPMENTAL BIOLOGY Romanian Journal of Morphology and Embryology Pub Date : 2023-10-01 DOI:10.47162/RJME.64.4.17

Victor Mihai Sacerdoţianu, Cecil Sorin Mirea, Petrică Popa, Dan Ionuţ Gheonea, Maria Camelia Foarfă, Marius Matei, Daniela Larisa Săndulescu, Cristian Virgil Lungulescu, Tudorel Ciurea, Bogdan Silviu Ungureanu

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Abstract

Background: Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors, mostly located within the stomach. About 30% of GISTs are incidentally diagnosed and as they become symptomatic may be associated with bleeding, bowel obstruction or spontaneous rupture.

Case presentation: We present the case of a middle-aged patient diagnosed with a giant gastric GIST, which presented for intermittent gastric outlet obstruction symptoms, and emphasize the major imagistic, histopathological, and therapeutic challenges that may be encountered. There are only several cases of gastric exophytic gastric GIST provoking intermittent gastric outlet obstruction. Tumor resection should be adapted to every patient's status, focused on en bloc extraction, with preservation of invaded organs as much as possible.

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巨大外生性胃肠道间质瘤（GIST）导致胃出口梗阻：病例报告和文献综述。

背景：胃肠道间质瘤（GIST）是一种罕见的间质肿瘤，主要位于胃部。大约 30% 的 GIST 偶然被诊断出来，当它们出现症状时，可能会伴有出血、肠梗阻或自发性破裂：我们介绍了一例因间歇性胃出口梗阻症状而被诊断为巨大胃 GIST 的中年患者的病例，并强调了可能遇到的主要影像学、组织病理学和治疗挑战。胃外生性胃 GIST 引发间歇性胃出口梗阻的病例仅有几例。肿瘤切除术应根据每位患者的情况而定，以整块切除为主，尽可能保留受侵器官。

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来源期刊

Romanian Journal of Morphology and Embryology DEVELOPMENTAL BIOLOGY-

CiteScore

1.70

自引率

20.00%

发文量

221

审稿时长

3-8 weeks

期刊介绍： Romanian Journal of Morphology and Embryology (Rom J Morphol Embryol) publishes studies on all aspects of normal morphology and human comparative and experimental pathology. The Journal accepts only researches that utilize modern investigation methods (studies of anatomy, pathology, cytopathology, immunohistochemistry, histochemistry, immunology, morphometry, molecular and cellular biology, electronic microscopy, etc.).