Comparative in-vitro evaluation of ebastine tablets (10 mg) available in bangladesh

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL Bangladesh Journal of Medical Science Pub Date : 2024-01-02 DOI:10.3329/bjms.v23i1.70673
S. Mimmi, Saqib Rahman, Prethula Areefin, Md. Shaki Mostaid, Md Ayman Siddique, Md Aminul Haque
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Abstract

Background: The symptoms of allergic responses, such as hay fever or urticaria, can be relieved with the use of ebastine, an efficient anti-allergic medication. Objective & Method: This study’s primary objective was to assess and contrast various quality control parameters, such as weight variation, % friability, hardness, disintegration time, dissolution profile, and potency, of the twelve different brands of Ebastine tablets that were readily available in Bangladesh in accordance with compendia procedures. It’s interesting to note that, according to various official requirements, all of the quality parameters indicated above were within acceptable bounds. Conclusion: Therefore, doctors can advise patients to use any of the Ebastine brands that are sold in Bangladesh. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 47-53
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孟加拉国现有依巴斯汀片(10 毫克)的体外比较评估
背景:使用高效抗过敏药物依巴斯汀可缓解花粉热或荨麻疹等过敏反应症状。目的和方法:本研究的主要目的是根据药典程序,评估和对比各种质量控制参数,如重量变化、易碎性%、硬度、崩解时间、溶解度曲线和药效,这些参数是孟加拉国现售的 12 种不同品牌的依巴斯汀片剂的质量控制参数。值得注意的是,根据各种官方要求,上述所有质量参数都在可接受范围内。结论因此,医生可以建议患者使用在孟加拉国销售的任何品牌的依巴斯汀。孟加拉国医学科学杂志》第 23 卷第 01 期 24 年 1 月 第 47-53 页
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来源期刊
Bangladesh Journal of Medical Science
Bangladesh Journal of Medical Science MEDICINE, GENERAL & INTERNAL-
CiteScore
1.70
自引率
55.60%
发文量
139
审稿时长
24 weeks
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