Nizar Ahmadieh, Toufic Zeidan, Celine Chaaya, David Cain, Marc Aoude, Anita Abouchahla, Hampig Raphael Kourie, Elie Nemer
{"title":"Biomarkers in Prostate Cancer: A Review.","authors":"Nizar Ahmadieh, Toufic Zeidan, Celine Chaaya, David Cain, Marc Aoude, Anita Abouchahla, Hampig Raphael Kourie, Elie Nemer","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Prostate cancer (PC) is the second most common cancer in men worldwide. It's the second leading cause cancer men in death. Prognostic tests based on molecular and biomarker analysis of tumor tissue may improve risk stratification of prostate cancer 2.</p><p><strong>Materials and methods: </strong>After a search on Pubmed for PC biomarkers, 72 papers responded to the objectives and will be included in the review.</p><p><strong>Results: </strong>A plethora of biomarkers are predictive for the prognosis of PC and its response to certain therapies, while others, once thought to be indicative of prognosis in PC, were not.</p><p><strong>Conclusions: </strong>This study can help in the development of diagnostic and prognostic tests of PC and contribute to the ongoing research into already existing tests.</p>","PeriodicalId":53633,"journal":{"name":"The gulf journal of oncology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The gulf journal of oncology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Prostate cancer (PC) is the second most common cancer in men worldwide. It's the second leading cause cancer men in death. Prognostic tests based on molecular and biomarker analysis of tumor tissue may improve risk stratification of prostate cancer 2.
Materials and methods: After a search on Pubmed for PC biomarkers, 72 papers responded to the objectives and will be included in the review.
Results: A plethora of biomarkers are predictive for the prognosis of PC and its response to certain therapies, while others, once thought to be indicative of prognosis in PC, were not.
Conclusions: This study can help in the development of diagnostic and prognostic tests of PC and contribute to the ongoing research into already existing tests.
背景：前列腺癌（PC）是全球第二大男性常见癌症。它是导致男性死亡的第二大癌症。基于肿瘤组织的分子和生物标志物分析的预后检测可改善前列腺癌的风险分层 2.材料与方法：在Pubmed上搜索PC生物标志物后，有72篇论文符合研究目标，将被纳入综述：结果：大量生物标志物可预测PC的预后及其对某些疗法的反应，而另一些曾被认为可预测PC预后的生物标志物却不能预测PC的预后：这项研究有助于开发 PC 的诊断和预后检测方法，并有助于对现有检测方法的持续研究。
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