Oral Isotretinoin Treatment in Rhinoplasty: A Review.

IF 0.9 Q3 SURGERY World Journal of Plastic Surgery Pub Date : 2023-01-01 DOI:10.61186/wjps.12.3.11
Mohamad Reza Afzalzadeh, Ali Alizadeh
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Abstract

The achievement of best outcome in rhinoplasty is very important for both of the patients and plastic surgeons. Since the skin characteristics (e.g. nasal thickness and sebaceous hypertrophy) has clear role on the result, many related interventions have been proposed in recent decades to gain an appropriate result. Accordingly, isotretinoin firstly introduced to treat some type of acne, has been suggested controversially to be used in rhinoplasty. Although the early uncertain studies implied on its side effects, the recent more powerful studies and evidences indicate that isotretinoin is remarkably effective to obtain proper outcome. Nevertheless, its prescription to patients need to be evaluated and personalized. More discussion on this regard are presented in the text.

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鼻整形术中的口服异维A酸治疗:综述。
实现鼻整形术的最佳效果对患者和整形外科医生来说都非常重要。由于皮肤特征(如鼻翼厚度和皮脂腺肥大)对手术效果有明显影响,近几十年来,人们提出了许多相关干预措施,以获得适当的手术效果。因此,异维A酸最初被用于治疗某种类型的痤疮,但也有人建议将其用于鼻整形术,这引起了争议。虽然早期的不确定研究暗示了其副作用,但最近更有力的研究和证据表明,异维A酸对获得适当的效果非常有效。尽管如此,仍需对患者的处方进行评估和个性化定制。文中将对此进行更多讨论。
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