Successfully Completed Laparoscopic Splenectomy for Young Woman With Immune Thrombocytopenic Purpura During Pregnancy in Reduced Port Surgery: A Case Study

Shigeaki Baba, Akira Sasaki, K. Otsuka, A. Umemura, T. Takahara, Y. Akiyama, T. Iwaya, H. Nitta, K. Koeda, Y. Kimura
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Abstract

Immune thrombocytopenic purpura (ITP) during pregnancy is a rare condition; however, it can lead to hemorrhagic complications due to gestational thrombocytopenia during delivery. A splenectomy is the treatment that will result in the highest complete remission rate for ITP and is sometimes required when thrombocytopenia is severe and fails to respond to medical treatment. Herein, we present a case of a patient who underwent a reduced port laparoscopic splenectomy (RPLS) for ITP during pregnancy. A 33-year-old female patient, who had past history of miscarriage at the 12th week of gestation and a stillbirth at the 36th week of gestation, was diagnosed with ITP at the 12th week of gestation. The patient received medical treatment, but the platelet count did not increase enough for spontaneous delivery. Therefore, a 3-port RPLS was scheduled at the 20th week of gestation following treatment with high-dose immunoglobulin therapy for 5 days. The patient was placed in the right semilateral position. The pneumoperitoneal pressure was set at 8 mmHg, which is lower than that used in a typical operation. The overall procedures were similar to those of a 4-port technique. There was no change in the fetal heart rate during or after the operation. The platelet counts increased and were maintained after the RPLS, and the course of the pregnancy was successful. The patient was able to deliver a healthy infant via vaginal delivery at the 37th week of gestation. In our experience, RPLS procedures offer high cosmetic satisfaction and are feasible and safe during the second trimester in pregnant women with ITP that does not respond well to medical treatments.
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为妊娠期免疫性血小板减少性紫癜的年轻女性成功完成腹腔镜脾切除术(缩口手术):病例研究
妊娠期免疫性血小板减少性紫癜(ITP)是一种罕见的疾病,但它可能会在分娩时因妊娠血小板减少而导致出血性并发症。脾脏切除术是使 ITP 完全缓解率最高的治疗方法,当血小板减少严重且药物治疗无效时,有时需要进行脾脏切除术。在此,我们将介绍一例在妊娠期接受缩孔腹腔镜脾切除术(RPLS)治疗 ITP 的患者。 一名 33 岁的女性患者既往曾在妊娠第 12 周流产,在妊娠第 36 周死胎,在妊娠第 12 周被诊断为 ITP。患者接受了药物治疗,但血小板计数没有增加到足以自然分娩的程度。因此,在接受了为期 5 天的大剂量免疫球蛋白治疗后,计划在妊娠第 20 周进行 3 孔 RPLS。患者被置于右半侧卧位。腹腔积气压力设定为 8 mmHg,低于一般手术使用的压力。整个手术过程与四孔技术相似。 手术中和手术后胎儿的心率没有变化。RPLS 术后血小板计数增加并保持不变,妊娠过程顺利。患者在妊娠第 37 周时经阴道分娩,产下一名健康婴儿。 根据我们的经验,对于药物治疗效果不佳的 ITP 孕妇,RPLS 手术具有很高的美容满意度,而且在妊娠后三个月是可行和安全的。
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