Subependymal giant cell astrocytoma as presentation of tuberous sclerosis: a case report

IF 0.7 Q4 CLINICAL NEUROLOGY Egyptian journal of neurosurgery Pub Date : 2024-01-30 DOI:10.1186/s41984-024-00263-y
P. S. Jayalakshmy, Aswathy Mohanachandran Pillai, Reshmi Rajan
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Abstract

A case of tuberous sclerosis patient on long-term follow-up is reported here. A 22-year-old female patient with epilepsy was diagnosed with tuberous sclerosis at the age of 12 years. At that time, a small subependymal giant cell astrocytoma has been detected along with the other signs of the disease. But the patient was not symptomatic of the intracranial lesion at that time. So, she was kept under follow-up with treatment for the epilepsy. Within 10 years, the lesion gradually enlarged and caused symptoms and the tumour had to be resected at the age of 22 years of age. Subependymal giant cell astrocytoma is very slow-growing low-grade tumour. If small and asymptomatic at the time of the initial diagnosis, resection is not advised. The patient should be kept under close follow-up.
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以结节性硬化症为表现的脐下巨细胞星形细胞瘤:一份病例报告
本文报告了一例长期随访的结节性硬化症患者。一名 22 岁的女性癫痫患者在 12 岁时被诊断为结节性硬化症。当时,患者被发现患有一个小的脐下巨细胞星形细胞瘤,并伴有其他病征。但患者当时并没有颅内病变的症状。因此,她在接受癫痫治疗的同时一直接受随访。10 年内,病灶逐渐扩大并引起症状,22 岁时不得不切除肿瘤。脐下巨细胞星形细胞瘤是一种生长非常缓慢的低级别肿瘤。如果肿瘤较小,且在初诊时无症状,则不建议切除。患者应接受密切随访。
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