Case Report: A Rare Case with Cutaneous Metastasis of Bladder Urothelial Carcinoma

Min-Jui Wu, Hui-Kung Ting, Ting-Ying Lee, Yu-Cing Jhuo
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Abstract

Bladder cancer is a common genitourinary malignancy with variable metastatic potential. Cutaneous metastasis is uncommon and often presents with a poor prognosis. We presented a 47-year-old man with a history of muscle-invasive urothelial carcinoma of the bladder and suffered from headache and right arm swelling that had persisted for months. The excisional biopsy of the skin lesions and scalp tumor showed high-grade metastatic carcinoma of urothelial origin. Even though is rare, cutaneous metastasis is still the possibility of urothelial carcinoma metastasis and mimics several types of skin lesions. There is no guideline for cutaneous metastases of urothelial carcinoma because of the small number of patients and poor prognoses. Chemotherapy remains the treatment of choice, and further studies are needed to assess the efficacy of immunotherapy for skin metastases of urothelial carcinoma.
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病例报告:膀胱尿路上皮癌皮肤转移的罕见病例
膀胱癌是一种常见的泌尿生殖系统恶性肿瘤,具有不同的转移可能性。皮肤转移并不常见,通常预后较差。我们接诊了一名 47 岁的男性患者,他曾患膀胱肌肉浸润性尿路上皮癌,头痛和右臂肿胀已持续数月。皮损和头皮肿瘤的切除活检显示为尿路上皮源性高级别转移癌。皮肤转移虽然罕见,但仍有可能是尿路上皮癌转移,并可模拟多种类型的皮肤病变。由于尿路上皮癌皮肤转移的患者较少且预后较差,目前还没有针对皮肤转移的指南。化疗仍是首选治疗方法,还需要进一步研究评估免疫疗法对尿路癌皮肤转移的疗效。
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