Long-term toxicities after allogeneic hematopoietic stem cell transplantation with or without total body irradiation: a population-based study in Korea

IF 17.7 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-16 DOI:10.3857/roj.2023.00871

J. Kwon, Byoung Hyuck Kim

引用次数: 0

Abstract

hypo-thyroidism (1.50; 95% CI, 1.1–2.1) were significantly increased after TBI. However, there were no significant differences in the occurrence of myocardial infarction and stroke according to TBI. Conclusions: Our results suggest that modern TBI may not additionally increase the risk of SC after allogeneic HSCT, although increased risks of other diseases were noted. Physicians should carefully consider individualized risks and benefits of TBI, with a particular focus by age group.

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同种异体造血干细胞移植后的长期毒性：韩国一项基于人群的研究

甲状腺功能减退（1.50；95% CI，1.1-2.1）在创伤性脑损伤后明显增加。不过，不同创伤性脑损伤导致的心肌梗死和中风的发生率没有明显差异。结论：我们的研究结果表明，现代创伤性脑损伤可能不会额外增加异基因造血干细胞移植后发生 SC 的风险，但其他疾病的风险有所增加。医生应仔细考虑 TBI 的个体化风险和益处，尤其要关注年龄组。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.