Association of Anthropometric Indices with Albumin to Creatinine Ratio and Glomerular Filtration Rate, as Indices of CKD: A Population-based Study.

IF 0.8 4区医学 Q4 UROLOGY & NEPHROLOGY Iranian journal of kidney diseases Pub Date : 2024-01-01

Firouzeh Moinzadeh, Media Babahajiani, Marjan Mansourian, Hourinaz Taghvaee

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Abstract

Introduction: This study was an attempt to detect the relationship between chronic kidney disease (CKD) and anthropometric indices in presence of confounding variables.

Methods: A cross-sectional study of 3375 participants was designed in Isfahan city. Waist-height ratio (WHtR), waist-hip ratio (WHR), body mass index (BMI) and waist circumference (WC) were measured. Participants were divided into CKD and non-CKD groups according to the calculated albumin to creatinine ratio (ACR) and estimated glomerular filtration rate (eGFR). Then, the groups were subdivided into sub-groups of high and normal anthropometric indices.

Results: To evaluate CKD in relation to anthropometric indices, odds ratio was calculated; in the female group, no association was observed (P ˃ .05). However, in the male group high levels of WHtR and BMI were associated with CKD (P value of .002 and .015, respectively). To evaluate the association between ACR and eGFR with anthropometric indices linear regression analysis was performed. There was no significant relation between ACR and eGFR with anthropometric indices in both sexes in a fully adjusted state (P ˃ .05).

Conclusion: High WHtR and BMI probably are associated with CKD in male. WHR and WC have no relation to the occurrence of CKD. There are no significant changes in regard to ACR and eGFR. DOI: 10.52547/ijkd.7685.

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作为慢性肾脏病指标的人体测量指标与白蛋白肌酐比值和肾小球滤过率的关系：一项基于人群的研究。

导言：本研究试图检测慢性肾脏病（CKD）与人体测量指数之间的关系：本研究试图在存在混杂变量的情况下，检测慢性肾脏病（CKD）与人体测量指数之间的关系：在伊斯法罕市对 3375 名参与者进行了横断面研究。研究测量了腰高比（WHtR）、腰臀比（WHR）、体重指数（BMI）和腰围（WC）。根据计算得出的白蛋白与肌酐比率（ACR）和估计肾小球滤过率（eGFR），将参与者分为慢性阻塞性肺病组和非慢性阻塞性肺病组。然后，各组又细分为人体测量指数高和正常的亚组：为了评估慢性肾功能衰竭与人体测量指数的关系，计算了几率比；在女性组中，没有观察到相关性（P ˃.05）。然而，在男性组中，高水平的 WHtR 和 BMI 与 CKD 相关（P 值分别为 .002 和 .015）。为了评估 ACR 和 eGFR 与人体测量指数之间的关系，我们进行了线性回归分析。在完全调整的状态下，男女患者的 ACR 和 eGFR 与人体测量指标之间没有明显关系（P ˃.05）：结论：高 WHtR 和 BMI 可能与男性慢性肾脏病有关。结论：高 WHtR 和 BMI 可能与男性慢性肾脏病有关，而 WHR 和 WC 与慢性肾脏病的发生无关。ACR和eGFR没有明显变化。 DOI: 10.52547/ijkd.7685.

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来源期刊

Iranian journal of kidney diseases UROLOGY & NEPHROLOGY-

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The Iranian Journal of Kidney Diseases (IJKD), a peer-reviewed journal in English, is the official publication of the Iranian Society of Nephrology. The aim of the IJKD is the worldwide reflection of the knowledge produced by the scientists and clinicians in nephrology. Published quarterly, the IJKD provides a new platform for advancement of the field. The journal’s objective is to serve as a focal point for debates and exchange of knowledge and experience among researchers in a global context. Original papers, case reports, and invited reviews on all aspects of the kidney diseases, hypertension, dialysis, and transplantation will be covered by the IJKD. Research on the basic science, clinical practice, and socio-economics of renal health are all welcomed by the editors of the journal.