Utilization of Nanogels Extract Leaf Binahong on Palatal Wound Healing

Chandra Lestari, Syafruddin Ilyas, Olivia Avriyanti Hanafiah
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Abstract

The palatal wound is difficult to heal related activity of eating and chewing, so needed system delivers drugs and materials that can help speed up the wound healing. Leaf binahong's content is saponins, tannins, alkaloids, flavonoids, and vitamin C. Content cause leaf binahong characteristic antibacterial, antiviral, anti-inflammatory, analgesic, and antioxidants important for wound healing. The preparation of nanogels in application biomedical and pharmacy has lots used, however, the use of nanogels leaf extract binahong still needs discussion more continue. Writing this aim to see the potency of nanogels extract leaf binahong to palatal mucosa wound healing was reviewed in various studies before. Several studies have disclosed that the use of nanogels and extract leaf binahong can speed up wound healing, both on the skin as well as in the cavity mouth through the enhancement of fibroblasts, collagen, and another factor. Based on the matter they can conclude that nanogels extract leaf binahong potentially speed up palatal mucosa wound healing.
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利用比纳红叶提取物纳米凝胶促进腭部伤口愈合
腭部伤口难以愈合与进食和咀嚼活动有关,因此需要系统输送有助于加速伤口愈合的药物和材料。叶槟榔中含有皂甙、单宁酸、生物碱、黄酮类化合物和维生素 C,这些成分具有抗菌、抗病毒、消炎、镇痛和抗氧化的特性,对伤口愈合非常重要。纳米凝胶的制备在应用生物医学和药学方面已经大量使用,然而,纳米凝胶的使用还需要更多的讨论。撰写此文的目的是为了了解纳米凝胶提取物叶binahong对腭粘膜伤口愈合的功效,之前的各种研究对此进行了回顾。一些研究表明,使用纳米凝胶和叶槟红提取物可以通过增强成纤维细胞、胶原蛋白和另一种因子加速皮肤和口腔内的伤口愈合。据此,他们可以得出结论,纳米凝胶提取物叶槟红可能会加速腭粘膜伤口愈合。
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