Maurizio Battaglia Parodi, Alessandro Arrigo, Emanuela Aragona, Adelaide Pina, Francesco Bandello
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引用次数: 0
Abstract
Purpose: To describe a phenotypical manifestation characterized by the identification of peripheral linear streaks associated with retinitis pigmentosa (RP).
Methods: Study design is a prospective observational case series. All consecutive patients affected by RP underwent a complete ophthalmological examination. The diagnosis of peripheral linear streaks was based on the identification of curvilinear atrophic streaks in the periphery of the retina.
Results: Overall, six out of 140 patients (4.2%) were affected by peripheral linear streaks associated with RP. A single patient showed also punched out chorioretinal lesions at the posterior pole, with macular neovascularization development over the follow-up, treated with ranibizumab injections.
Conclusions: RP phenotypical manifestation characterized by peripheral linear streaks is infrequent and may provide additional evidence to support the contribution of inflammation in the pathogenesis of RP.
目的:描述一种与视网膜色素变性(RP)相关的表型表现,其特征是发现周边线状条纹:研究设计为前瞻性观察病例系列。所有连续的 RP 患者都接受了全面的眼科检查。外周线状条纹的诊断依据是视网膜外周出现的曲线状萎缩条纹:总的来说,140 名患者中有 6 名(4.2%)患有与视网膜退行性病变相关的周边线状条纹。一名患者的视网膜后极部还出现了打孔的脉络膜病变,随访期间黄斑新生血管也有所发展,该患者接受了雷尼珠单抗注射治疗:结论:以外周线性条纹为特征的 RP 表型表现并不常见,可为支持炎症在 RP 发病机制中的作用提供更多证据。
期刊介绍:
The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.