{"title":"Pyolytics: A Step Forward to Address Respiratory Hypoxia in Coronavirus\nInfection","authors":"Ilnur Yagudin, Darya Suntsova","doi":"10.2174/0122113525287737240201050550","DOIUrl":null,"url":null,"abstract":"\n\nRespiratory failure and increasing hypoxia in the era of coronavirus infection is the\ncause of fatal outcomes in patients with SARS. The bronchoalveolar obstruction prevents the\nnormal passage of air, resulting in decreased oxygenation. The available methods of oxygenation\n(ECMO) are often not cost-effective and are not readily available in pandemic settings.\nHence, the search for alternatives has prompted the discovery of a new pharmacological group\n- pyolytics, the use of which is very promising due to its simplicity and availability.\n","PeriodicalId":7951,"journal":{"name":"Anti-Infective Agents","volume":"45 10","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anti-Infective Agents","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/0122113525287737240201050550","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Respiratory failure and increasing hypoxia in the era of coronavirus infection is the
cause of fatal outcomes in patients with SARS. The bronchoalveolar obstruction prevents the
normal passage of air, resulting in decreased oxygenation. The available methods of oxygenation
(ECMO) are often not cost-effective and are not readily available in pandemic settings.
Hence, the search for alternatives has prompted the discovery of a new pharmacological group
- pyolytics, the use of which is very promising due to its simplicity and availability.
期刊介绍：
Anti-Infective Agents publishes original research articles, full-length/mini reviews, drug clinical trial studies and guest edited issues on all the latest and outstanding developments on the medicinal chemistry, biology, pharmacology and use of anti-infective and anti-parasitic agents. The scope of the journal covers all pre-clinical and clinical research on antimicrobials, antibacterials, antiviral, antifungal, and antiparasitic agents. Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health services.
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