A Mystery Unsolved: A Spontaneous Lens and Uveal Prolapse in a New-born

NABILA ALJUFRI, Shafiq Advani, Dany Petra, Agnesstacia Vania L, Yulia Aziza, Julie D Barliana, Rio Rhendy
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Abstract

Introduction : Corneal rupture in new-born, especially during the first week of life is rare. Some of these cases occur because of ocular trauma during deliveries, systemic infection, and congenital anomalies. We aim to deliver a rare case of spontaneous lens and uveal prolapse in new-born and management in treating the case. Case Illustration : A-2-day-old full-term-baby was referred due to bleeding of the right eye 6 hours post-partum by spontaneous vaginal delivery with no trauma. The mother, a 23-year-old, having the second born with no history of medical illness or vaginal discharged during pregnancy. Measurements of birth weight and length were normal. Eye examination of the right eye (RE) was uveal and lens prolapse and left eye (LE) cloudy cornea with leukoma and prominent neovascularization. Orbital CT-Scan revealed bilateral vitreous bleeding of both eyes. Laboratory examination showed reactive IgM for herpes simplex virus, reactive IgG for both toxoplasma and rubella. Corneal swab culture was sterile. Systemic and topical antibiotics were administered then switched to systemic antivirus. The 12-day-old-patient showed partial epithelization of cornea, less uveal volume with it partially shrank. Close observation was conducted and evisceration was postponed. Discussion : Although etiologic work-up has been addressed, exact etiology remains unknown with the possibility of congenital cause. It has been postulated that structurally malformed eyes are more prone to corneal perforations. Management should be personalized based on the patient’s need. Conclusion : Thorough examination is vital a rare case with undisclosed aetiology especially new-born. Patient monitoring is sufficient if no infections and bleedings found.
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未解之谜新生儿自发性透镜和葡萄膜脱垂
导言:新生儿角膜破裂,尤其是出生后一周内的新生儿角膜破裂十分罕见。其中一些病例是由于分娩过程中的眼外伤、全身感染和先天畸形造成的。我们旨在介绍一例罕见的新生儿自发性晶状体和葡萄膜脱垂病例及治疗方法。病例说明:一名 2 天大的足月婴儿因产后 6 小时右眼出血而转诊,她是在无外伤的情况下经阴道自然分娩的。产妇 23 岁,是第二胎,无疾病史或孕期阴道排液史。出生体重和身长测量正常。右眼(RE)眼底检查为葡萄膜和晶状体脱垂,左眼(LE)角膜混浊,有白细胞瘤和突出的新生血管。眼眶 CT 扫描显示双眼玻璃体出血。实验室检查显示,单纯疱疹病毒 IgM 反应性,弓形虫和风疹 IgG 反应性。角膜拭子培养无菌。患者接受了全身和局部抗生素治疗,随后转为全身抗病毒治疗。12 天大的患者角膜上皮部分脱落,葡萄膜体积缩小,部分萎缩。对患者进行了密切观察,并推迟了切除手术。讨论:虽然已经进行了病因检查,但确切的病因仍然不明,有可能是先天性的。有人推测,结构畸形的眼睛更容易发生角膜穿孔。应根据患者的需要进行个性化治疗。结论:对于病因不明的罕见病例,尤其是新生儿,彻底检查至关重要。如果没有发现感染和出血,对患者进行监测就足够了。
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