Fabrication and Characterization of Fast Dissolving Herbal Buccal Film Containing Mimosa Pudica Leaf Extract

Abstract

Buccal films has distinct advantages over conventional dosage forms. Drugs can be delivered through buccal route, by avoiding first pass metabolism to produce local and systemic action. Rapid absorption of the drug is achieved because buccal mucosa is highly permeable with rich blood supply. Only few dosage forms are designed to deliver the drug through this route. Leaf extract of Mimosa pudica has number of pharmacological actions. Buccal film of leaf extract of mimosa pudica is prepared by solvent casting method and evaluated for its characteristics. Six formulations were prepared, out of which F3 formulation was found promising formulation, releases 96.13% of drug in 10 minutes.