Amadeo Pesce, Katie Bollman, Kevin Krock, A. Cua, Keith Tran, Richard Thomas
{"title":"Monitoring buprenorphine in patients on medication-assisted treatment","authors":"Amadeo Pesce, Katie Bollman, Kevin Krock, A. Cua, Keith Tran, Richard Thomas","doi":"10.5055/jom.0844","DOIUrl":null,"url":null,"abstract":"Background: Buprenorphine is used for medication-assisted treatment of opioid dependence. \nPurpose: Monitoring of medication adherence involves testing of urine or oral fluid for the drug or its metabolite. \nMethods: Quantitative results using liquid chromatography tandem mass spectrometer testing defined the excretion pattern of the drug and its metabolites. \nResults: Frequency distribution curves of buprenorphine and norbuprenorphine describe the expected drug concentrations of patients on this medication. \nConclusion: Urine and oral fluid drug testing can be used to monitor adherence in this population.","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":" 47","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of opioid management","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5055/jom.0844","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Buprenorphine is used for medication-assisted treatment of opioid dependence.
Purpose: Monitoring of medication adherence involves testing of urine or oral fluid for the drug or its metabolite.
Methods: Quantitative results using liquid chromatography tandem mass spectrometer testing defined the excretion pattern of the drug and its metabolites.
Results: Frequency distribution curves of buprenorphine and norbuprenorphine describe the expected drug concentrations of patients on this medication.
Conclusion: Urine and oral fluid drug testing can be used to monitor adherence in this population.
期刊介绍:
The Journal of Opioid Management deals with all aspects of opioids. From basic science, pre-clinical, clinical, abuse, compliance and addiction medicine, the journal provides and unbiased forum for researchers and clinicians to explore and manage the complexities of opioid prescription.