Mapping the Therapeutic Options for Multiple Sclerosis in Brazil: A Comprehensive Analysis

Sclerosis Pub Date : 2024-02-06 DOI:10.3390/sclerosis2010003
C. S. Desidério, Yago Marcos Pessoa-Gonçalves, R. O. Trevisan, Marlos Aureliano Dias-Sousa, Weslley Guimarães Bovi, Wellington Francisco Rodrigues, Marcos Vinícius da Silva, V. R. Júnior, Carlo José Freire Oliveira
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Abstract

Multiple sclerosis is an autoimmune disease that affects the central nervous system. In Brazil, there are currently several therapeutic options for the treatment of this condition, with some being distributed free of charge, while others are not included in the list of free medications. The objective of this article is to provide a pharmacoepidemiological analysis of the available medications in the country, covering their mechanisms of action, the historical context of approval and free distribution within the healthcare system, and their geographical distribution of application. Additionally, we discuss the impact of the inclusion of these medications on hospitalization and mortality rates in the country. We hope that this work serves as a resource for healthcare professionals to better understand pharmacoepidemiology and for health policymakers seeking data for the planning of public policies aimed at the treatment of multiple sclerosis.
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绘制巴西多发性硬化症治疗方案图:综合分析
多发性硬化症是一种影响中枢神经系统的自身免疫性疾病。在巴西,目前有几种治疗这种疾病的方法,其中一些是免费发放的,而另一些则不在免费药物之列。本文旨在对巴西现有的药物进行药物流行病学分析,分析内容包括药物的作用机制、在医疗保健系统内获得批准和免费发放的历史背景,以及药物应用的地理分布。此外,我们还讨论了纳入这些药物对该国住院率和死亡率的影响。我们希望这项工作能成为医疗保健专业人员更好地了解药物流行病学的资源,也能为卫生政策制定者提供数据,帮助他们规划旨在治疗多发性硬化症的公共政策。
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