Case Report: Temporary pacing using active fixation lead and invasive electrophysiology studies for immune checkpoint inhibitor associated reversible advanced atrioventricular block

Yifan Wang, Min Qian, Xiaofeng Jin, Jiaqi Wang, Tai-bo Chen, Peng Gao, Zhongwei Cheng, Jinzhi Lai, Yongtai Liu, Jingbo Fan, Lihua Zhang, Kangan Cheng, H. Deng, Quan Fang, Deyan Yang
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Abstract

A case of immune checkpoint inhibitors (ICIs)-associated myocarditis with reversible advanced atrioventricular block (AVB) was reported. We innovatively used active fixation lead connected to an external device for prolonged temporary pacing until atrioventricular conduction recovered. Invasive electrophysiology studies were performed to evaluate atrioventricular conduction in detail. Long-term follow-up for nearly 120-days and repeated long-term electrocardiography was conducted to ensure the conduction system was truly recovered.
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病例报告:使用有源固定导联进行临时起搏和侵入性电生理学研究治疗免疫检查点抑制剂相关的可逆性晚期房室传导阻滞
报告了一例免疫检查点抑制剂(ICIs)相关心肌炎伴可逆性晚期房室传导阻滞(AVB)的病例。我们创新性地使用了与外部装置相连的有源固定导联进行长时间临时起搏,直至房室传导恢复。我们进行了有创电生理学研究,以详细评估房室传导。进行了近 120 天的长期随访和反复的长期心电图检查,以确保传导系统真正恢复。
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