Influence of periodontal treatment on rheumatoid arthritis clinical parameters

Gabriela Spanholi Tamagno, C. Nassar, Marcio Augusto Nogueira, Myllenah Marrahyllah Simão Monteiro, P. Nassar
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Abstract

Periodontitis is a common chronic inflammatory disease characterized by destruction of tooth-supporting tissues, including alveolar bone, periodontal ligament, and cementum. It is the leading cause of dental loss and is considered one of the two biggest threats to oral health (Zhao et al., 2018). Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease characterized by swelling of the joints, joint tenderness, and destruction of the synovial joints, leading to severe incapacitation and premature mortality as it involves systemic effects. Both have been related, because the severity of RA is greater in patients with the first disease (Mercado et al., 2001) and Porphyromonas gingivalis, is also identified in synovial fluid and not only in damaged periodontal tissue. The proposed research was a prospective clinical trial with a quantitative approach carried out in the dental clinic of UNIOESTE in 90 days with 20 patients suffering from the autoimmune disease. Improvements in the disease were noted by means of analysis by the T, DAS 28 and VAS tests when the periodontal suitability was chosen.
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牙周治疗对类风湿性关节炎临床参数的影响
牙周炎是一种常见的慢性炎症性疾病,以牙槽骨、牙周韧带和牙骨质等牙齿支持组织的破坏为特征。它是牙齿脱落的主要原因,被认为是口腔健康的两大威胁之一(Zhao et al.)类风湿性关节炎(RA)是一种慢性自身免疫性炎症疾病,以关节肿胀、关节触痛和滑膜关节破坏为特征,由于涉及全身影响,会导致严重的丧失工作能力和过早死亡。这两种疾病都与牙龈卟啉单胞菌(Porphyromonas gingivalis)有关,因为患有第一种疾病的患者患 RA 的严重程度更高(Mercado 等人,2001 年),而且牙龈卟啉单胞菌也在滑液中被发现,而不仅仅是在受损的牙周组织中。拟议的研究是一项前瞻性临床试验,在 UNIOESTE 的牙科诊所对 20 名自身免疫性疾病患者进行了为期 90 天的定量研究。通过T、DAS 28和VAS测试分析发现,在选择牙周适合度时,疾病得到了改善。
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