Sports-Statin Interaction: Ensuring Safe and Smart Synergy

Dr Sanjay Kalra, Dr Suneet Verma, Dr KAMAL KISHOR
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Abstract

Both sports (physical activity) and statins are recommended for the prevention and management of atherosclerotic cardiovasculardisease. The synergy that they create in risk reduction, however, may turn dysfunctional at times. Statin usage is associated witha risk of muscle-related conditions including myalgia, myositis and rhabdomyolysis. This risk is exacerbated by unaccustomedphysical activity, exercise or sports. The communication shares practical and pragmatic suggestions regarding the preventionand management of the potential sports-statin interactions that may occur. It also highlights the need to consider drug-lifestyleinteractions, apart from conventional drug-drug interactions.
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运动与胰岛素的相互作用:确保安全和智能的协同作用
运动(体育锻炼)和他汀类药物都被推荐用于预防和治疗动脉粥样硬化性心血管疾病。然而,它们在降低风险方面的协同作用有时可能会失灵。服用他汀类药物会导致肌肉相关疾病的风险,包括肌痛、肌炎和横纹肌溶解症。不习惯的体力活动、锻炼或运动会加剧这种风险。本通报分享了有关预防和管理可能发生的运动与他汀相互作用的实用而务实的建议。它还强调,除了传统的药物与药物之间的相互作用外,还需要考虑药物与生活方式之间的相互作用。
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