[Examination of Urinary Sediment in a Patient with Lupus-Like HIV-Associated Immune Complex Kidney Disease (HIVICK) - Case Report and Review of the Literature].

Gianmarco Borriello, Michelangelo Nigro, Pierluigi D'Angiò, Simona Laurino, Andrea Gigliotti, Davide Viggiano, Giuseppe Gigliotti
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Abstract

Renal involvement is very common in patients with HIV infection. The phenotype varies from the most frequently "collapsing" variant of focal and segmental glomerulosclerosis (FSGS) to "lupus-like HIV-immune complex kidney disease" (HIVICK). The latter is characterized by a histological picture that recalls lupus nephropathy. Through a clinical case, we underline the importance of urinary sediment analysis in patients with suspected glomerulopathy. Findings such as the characteristic cells that show the typical appearance of Herpes virus (HSV) infection or LE cells have significantly supported the diagnosis of HIVICK. In light of the present observations, we suggest systematically carrying out a cytological examination of the urinary sediment to confirm diagnostic hypotheses of rare pathologies.

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[狼疮样艾滋病相关免疫复合物肾病(HIVICK)患者的尿沉渣检查--病例报告和文献综述]。
肾脏受累在艾滋病毒感染患者中非常常见。其表现型多种多样,从最常见的 "塌陷 "型局灶性和节段性肾小球硬化症(FSGS)到 "狼疮样艾滋病免疫复合物肾病"(HIVICK)。后者的组织学特征与狼疮肾病相似。通过一个临床病例,我们强调了对疑似肾小球病变患者进行尿沉渣分析的重要性。诸如显示疱疹病毒(HSV)感染典型表现的特征性细胞或 LE 细胞等发现,都为 HIVICK 的诊断提供了重要支持。鉴于目前的观察结果,我们建议系统地对尿沉渣进行细胞学检查,以确认罕见病变的诊断假设。
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来源期刊
CiteScore
0.70
自引率
0.00%
发文量
62
期刊介绍: Il Giornale Italiano di Nefrologia (GIN) è la rivista di educazione continua della Società Italiana di Nefrologia SIN ed è pubblicato bimestralmente. E" il più autorevole organo di informazione nefrologia disponibile a livello nazionale. Il giornale Italiano di Nefrologia offre la più aggiornata informazione medico-scientifica rivolta al nefrologo sotto forma di rassegne, casi clinici e articoli finalizzati all’Educazione Continua in Medicina, oltre ai notiziari ed agli atti dei congressi di questa prestigiosa Società Scientifica
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