Treatment of canine perineal hernia with a fascia lata graft is noninferior to the elevation of the internal obturator muscle: a prospective randomized trial of 66 dogs.

IF 1.6 2区 农林科学 Q2 VETERINARY SCIENCES Javma-journal of The American Veterinary Medical Association Pub Date : 2024-03-07 Print Date: 2024-05-01 DOI:10.2460/javma.23.11.0650
Tuuli M Åhlberg, Kati Salla, Outi M Laitinen-Vapaavuori, Sari H Mölsä
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Abstract

Objective: To compare the recurrence rate after herniorrhaphy of canine perineal hernia (PH) using elevation of the internal obturator muscle (EIOM) or fascia lata graft (FLG) and assess how clinical signs related to defecation evolve during 12 months postoperatively.

Animals: 66 client-owned male dogs undergoing PH surgery between March 1, 2017, and December 31, 2020.

Methods: Dogs were randomized into 2 groups (EIOM = 36; FLG = 30) applying 2 stratification factors: preoperative bladder location and the defecation signs score (DSS). Follow-up visits were at 2 weeks and 3, 6, and 12 months postoperatively. The main outcome, the recurrence of PH was evaluated by rectal examination. We evaluated the noninferiority of FLG to EIOM from the difference in recurrence proportions between the techniques (95% CI), comparing the CI with a pre-defined noninferiority margin (15%). To evaluate defecation signs, the DSS was calculated from the owner questionnaire and assessed with a linear mixed model (P < .05 significant).

Results: In 63 dogs attending the 12-month follow-up, the recurrence rate was 8.8% (3/34) in the EIOM and 10.3% (3/29) in the FLG group. The CI (-11.94% to 14.99%) was below the pre-defined margin, indicating the noninferiority of FLG. After surgery, the DSS decreased (P < .001), remaining low during the follow-up.

Clinical relevance: FLG was non-inferior to EIOM when considering recurrence. The DSS decreased postoperatively and complications were uncommon. FLG is a useful alternative for the treatment of canine PH.

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用筋膜移植治疗犬会阴部疝气的效果并不亚于抬高腹股沟内肌:对 66 只犬进行的前瞻性随机试验。
目的比较使用提肛肌内肌(EIOM)或筋膜移植(FLG)对犬周疝(PH)进行疝成形术后的复发率,并评估与排便相关的临床症状在术后12个月内的变化情况。动物:在2017年3月1日至2020年12月31日期间接受PH手术的66只客户饲养的雄性犬:根据术前膀胱位置和排便体征评分(DSS)这两个分层因素,将犬随机分为 2 组(EIOM = 36;FLG = 30)。随访时间为术后 2 周、3、6 和 12 个月。主要结果是通过直肠检查评估 PH 的复发情况。我们根据两种技术复发比例的差异(95% CI)来评估FLG与EIOM的非劣效性,并将CI与预先设定的非劣效性差值(15%)进行比较。为了评估排便症状,根据狗主问卷计算了DSS,并用线性混合模型进行了评估(P < .05显著):在 63 只接受了 12 个月随访的狗中,EIOM 组的复发率为 8.8%(3/34),FLG 组为 10.3%(3/29)。CI值(-11.94%至14.99%)低于预设值,表明FLG不具劣势。术后,DSS下降(P < .001),在随访期间保持在较低水平:临床相关性:考虑到复发因素,FLG并不优于EIOM。临床相关性:考虑到复发因素,FLG疗效并不优于EIOM,术后DSS下降,并发症也不常见。FLG是治疗犬PH的有效替代方法。
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来源期刊
CiteScore
1.60
自引率
15.80%
发文量
539
审稿时长
6-16 weeks
期刊介绍: Published twice monthly, this peer-reviewed, general scientific journal provides reports of clinical research, feature articles and regular columns of interest to veterinarians in private and public practice. The News and Classified Ad sections are posted online 10 days to two weeks before they are delivered in print.
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