Myofascial junction: Emerging insights into the connection between deep/muscular fascia and muscle

IF 2.3 4区医学 Q1 ANATOMY & MORPHOLOGY Clinical Anatomy Pub Date : 2024-03-12 DOI:10.1002/ca.24148

Carmelo Pirri, Lucia Petrelli, Diego Guidolin, Andrea Porzionato, Caterina Fede, Veronica Macchi, Raffaele De Caro, Carla Stecco

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Abstract

Muscles and fasciae are mutually connected and are influenced by force transmission. However, the anatomical connectivity and histological features of these structures remain unclear. The aim of this study was to assess the evidence for connection between muscles and deep/muscular fasciae. We assessed this relationship in different topographical regions of human cadavers and in mice. The results showed that myofascial junctions (MFJ) were made up of collagen I immune-positive structures occupying an average area of 5.11 ± 0.81 μm², distributed in discrete regions at the interface between muscle and fascia with an average density of 9.7 ± 2.51 MFJ/mm and an average inclination angle of 35.25 ± 1.52°. These specialized structures also showed collagen III and HA immunopositivity and the presence of elastic fibers. The human myofascial junction can be visualized, opening emerging insights into the connection between deep/muscular fascia and muscle.

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肌筋膜交界处：对深层/肌肉筋膜与肌肉之间联系的新认识。

肌肉和筋膜相互连接，并受力传递的影响。然而，这些结构的解剖连接和组织学特征仍不清楚。本研究旨在评估肌肉与深层/肌肉筋膜之间联系的证据。我们在人类尸体和小鼠的不同地形区域评估了这种关系。结果显示，肌筋膜连接（MFJ）由胶原 I 免疫阳性结构组成，平均面积为 5.11 ± 0.81 μm2，分布在肌肉和筋膜界面的离散区域，平均密度为 9.7 ± 2.51 MFJ/mm，平均倾斜角度为 35.25 ± 1.52°。这些特殊结构还显示出胶原蛋白 III 和 HA 免疫阳性以及弹性纤维的存在。人体肌筋膜交界处的可视化，使人们对深层/肌肉筋膜与肌肉之间的联系有了新的认识。

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来源期刊

Clinical Anatomy 医学-解剖学与形态学

CiteScore

5.50

自引率

12.50%

发文量

154

审稿时长

3 months

期刊介绍： Clinical Anatomy is the Official Journal of the American Association of Clinical Anatomists and the British Association of Clinical Anatomists. The goal of Clinical Anatomy is to provide a medium for the exchange of current information between anatomists and clinicians. This journal embraces anatomy in all its aspects as applied to medical practice. Furthermore, the journal assists physicians and other health care providers in keeping abreast of new methodologies for patient management and informs educators of new developments in clinical anatomy and teaching techniques. Clinical Anatomy publishes original and review articles of scientific, clinical, and educational interest. Papers covering the application of anatomic principles to the solution of clinical problems and/or the application of clinical observations to expand anatomic knowledge are welcomed.