Regression of Intermediate-High Risk Monoclonal Gammopathy of Undetermined Significance (MGUS) With Long-term Use of Curcumin: A Case Report.

IF 2.9 3区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Integrative Cancer Therapies Pub Date : 2024-01-01 DOI:10.1177/15347354241242099
Terry Golombick, Rajeev Ramakrishna, Arumugam Manoharan
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Abstract

Patients with intermediate-high risk MGUS are not offered therapeutic options to date and standard of care remains observation with re-evaluations of the patient every 3 to 6 months. Given the persistent risk of progression as well as potential complications experienced by some, and anxiety experienced by most patients, early intervention with non-toxic curcumin, aimed at potentially slowing down or stopping disease progression might be therapeutic. We present here an intermediate-high risk MGUS patient who has been taking curcumin for 16 years and has shown a decrease in disease markers and an increase in uninvolved immunoglobulins, adding to the body of evidence of benefit of curcumin to MGUS patients.

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长期服用姜黄素可缓解中高风险的意义未定单克隆性腺病(MGUS):病例报告。
迄今为止,中高风险的 MGUS 患者还没有治疗方案,标准的治疗方法仍然是观察,每 3 到 6 个月对患者进行一次重新评估。考虑到病情恶化的持续风险、部分患者可能出现的并发症以及大多数患者的焦虑情绪,使用无毒姜黄素进行早期干预,可能会减缓或阻止病情恶化。我们在此介绍一位已服用姜黄素 16 年的中高危 MGUS 患者,该患者的疾病标志物有所下降,未受累的免疫球蛋白有所增加,这为姜黄素对 MGUS 患者的益处提供了更多证据。
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来源期刊
Integrative Cancer Therapies
Integrative Cancer Therapies 医学-全科医学与补充医学
CiteScore
4.80
自引率
3.40%
发文量
78
审稿时长
>12 weeks
期刊介绍: ICT is the first journal to spearhead and focus on a new and growing movement in cancer treatment. The journal emphasizes scientific understanding of alternative medicine and traditional medicine therapies, and their responsible integration with conventional health care. Integrative care includes therapeutic interventions in diet, lifestyle, exercise, stress care, and nutritional supplements, as well as experimental vaccines, chrono-chemotherapy, and other advanced treatments. Contributors are leading oncologists, researchers, nurses, and health-care professionals.
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