Extensive Hepatic Infarction due to Polycythemia Vera.

Kazuhiro Furukawa, Fumihiro Urano, Shozo Okamura, Hiroki Kawashima
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Abstract

Polycythemia vera (PV) is one of the three BCR-ABL1-negative myeloproliferative neoplasms characterized by activating mutations in JAK2, which clinically presents as erythrocytosis and has an increased risk of both thromboembolic events and progression to myelofibrosis and acute myeloid leukemia. Splanchnic vein thrombosis is a rare manifestation of venous thromboembolism involving one or more abdominal vessels and is strongly associated with PV. We herein report a case in which hepatic infarction due to PV was saved by conservative treatment.

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多血细胞瘤引起的广泛肝梗塞
多发性红细胞增多症(PV)是三种 BCR-ABL1 阴性骨髓增殖性肿瘤之一,其特征是 JAK2 发生活化突变,临床表现为红细胞增多症,血栓栓塞事件以及发展为骨髓纤维化和急性髓性白血病的风险都会增加。脾静脉血栓形成是一种罕见的静脉血栓栓塞表现,累及一条或多条腹腔血管,与左心室积水密切相关。我们在此报告一例通过保守治疗挽救了因腹腔静脉栓塞导致的肝梗死的病例。
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