Imaging features and surgical management of giant parathyroid adenoma with autoinfarction

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-03-26 DOI:10.25259/jcis_133_2023
Tapan Patel, Rachelle Wolk, N. Cipriani, Elizabeth A. Blair, D. Ginat
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Abstract

Autoinfarction of a parathyroid adenoma can have an atypical clinicoradiologic features that can mimic an inflammatory process or malignancy. In addition, the associated fibrosis makes surgical resection more challenging than for regular parathyroid adenomas. The implications of these findings are that while autoinfarction of parathyroid adenomas is a rare phenomenon, this entity should be considered when there are heterogeneous and cystic components on imaging in patients without hypercalcemia. Ultimately, histopathology is necessary for definitive diagnosis.
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伴有自身梗死的巨大甲状旁腺腺瘤的影像特征和手术治疗
甲状旁腺腺瘤的自身梗死可能具有非典型的临床和放射学特征,可以模仿炎症过程或恶性肿瘤。此外,与普通的甲状旁腺腺瘤相比,相关的纤维化使得手术切除更具挑战性。这些发现的意义在于,虽然甲状旁腺腺瘤的自身梗死是一种罕见现象,但当无高钙血症的患者出现影像学上的异质性和囊性成分时,就应考虑到这一实体。最终,组织病理学检查是明确诊断的必要条件。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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