Problematic issues of prevention and precise control of diseases associated with hypoxia

Andrey V. Lyubimov
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Abstract

Cardiovascular diseases are the one of the main causes of death in the 21st century. Their rating is not expected to be decreased in the near future despite all the successes in the wide distribution and using of high-tech methods of treatment. This article is devoted to the problem of introducing fundamental recent discoveries into practical medicine as part of the development of preventive, personalized and precision medicine. The author considers not used mechanisms of endogenous adaptation, prevention and preclinical diagnosis of hypoxia-associated diseases in the clinic and concludes that introducing of a new marker of adaptation to visceral hypoxemia is perspective approach in therapy of the cardiovascular diseases.
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预防和精确控制与缺氧有关的疾病的难题
心血管疾病是 21 世纪的主要死亡原因之一。尽管在广泛传播和使用高科技治疗方法方面取得了巨大成功,但预计在不久的将来,心血管疾病的发病率不会下降。这篇文章专门探讨了在发展预防医学、个性化医学和精准医学的过程中,如何将最新的基本发现引入实用医学的问题。作者考虑了临床中尚未使用的内源性适应机制、低氧相关疾病的预防和临床前诊断,并得出结论:引入内脏低氧血症适应的新标志物是治疗心血管疾病的一种新方法。
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