An experimental study to evaluate galactagogue activity of Bidali (Dioscorea pentaphylla Linn.) with special reference to Stanya Janana

Akshatha Somayaji, Giri Prashath K G, Suresh Janadri, Shiva Manjunath M P, Seema Pradeep, Manjunath P Mudagal
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Abstract

More than 8 Lakh infantile deaths in India are attributed to inadequate breastfeeding, which is correlated with a prevalence of 45% to 53.6% cases of oligogalactia. Bidali (Dioscorea pentaphylla Linn.) is one among the two varieties of Vidari as described by Acharya Dalhana, with Stanya Vardhaka Karma. Hence the experimental evaluation of galactagogue activity of Bidali (Dioscorea pentaphylla Linn.) was carried out using milk estimation by the means of pup weight and weight gain along with estimation of serum prolactin and histology of breast tissue. Assessment was done by dam weight, daily milk yield by the means of pup weight and weight gain, serum prolactin estimation and histology of breast issue. The treatment groups have shown positive result in dose dependent manner in the parameters; Weight of Dams, and Weight of Pups. Histology reports re-emphasize the same; the development of Tubulo-alveolar unit and intraluminal secretions were more in group treated with higher dose than that of group treated with lower dose of Bidali (Dioscorea pentaphylla Linn.).
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评估比达里(Dioscorea pentaphylla Linn.)促乳汁分泌活性的实验研究,特别关注 Stanya Janana
印度有 80 多万名婴儿死于母乳喂养不足,这与 45%至 53.6%的少乳症发病率有关。Bidali(Dioscorea pentaphylla Linn.)是阿查里亚-达尔哈纳(Acharya Dalhana)描述的两个维达里(Vidari)品种之一,具有 Stanya Vardhaka Karma 特性。因此,对 Bidali(Dioscorea pentaphylla Linn.)通过幼崽体重和增重、血清催乳素估测和乳房组织学检查,对母鼠体重、日产奶量进行评估。治疗组在母鼠体重和幼鼠体重等参数上都显示出与剂量相关的积极效果。组织学报告再次强调了这一点:使用高剂量比达力(Dioscorea pentaphylla Linn.)
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