Recent Advancements and Biological Activities of Triazole Derivatives: a Short Review

Abstract

Many heterocyclic triazole rings and compounds containing triazole rings exhibit diverse biological activities. Heterocyclic derivatives of this class possess significant value for the discovery and development of new anticonvulsant medications as a result of successful synthesis of various triazole derivatives that hit the market for pharmaceuticals as CNS stimulants. The two isomers of triazole containing derivatives are 1,2,3-trizoles and 1,2,4-triazoles. From these two, 1, 2,4-triazole containing drugs exhibit a variety of pharmacological effects, including antimycobacterial, antitubercular, anticancer, anticonvulsant and herbicidal properties. Consequently, triazole-containing molecules function as potentially effective drug and may be useful for the design and development of new triazole derivatives that could be more efficacious and less toxic. This review summarizes data on various triazole derivatives and their significance.