Self-micellizing solid dispersion of thymoquinone with enhanced biopharmaceutical and nephroprotective effects

IF 6.5 2区医学 Q1 PHARMACOLOGY & PHARMACY Drug Delivery Pub Date : 2024-04-08 DOI:10.1080/10717544.2024.2337423

Shimul Halder, Sanjida Afrose, Manik Chandra Shill, Nahid Sharmin, Patricia Prova Mollick, Madhabi Lata Shuma, Md. Abdul Muhit, S. M. Abdur Rahman

引用次数: 0

Abstract

The present study was designed to develop a self-micellizing solid dispersion (SMSD) containing Thymoquinone (TQM), a phytonutrient obtained from Nigella sativa seeds, aiming to improve its biophar...

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具有增强生物制药和肾脏保护作用的胸腺醌自胶化固体分散体

本研究旨在开发一种含有胸腺醌（TQM）的自胶凝固体分散体（SMSD），胸腺醌是从黑麦草种子中提取的一种植物营养素，目的是改善其生物亲和性。

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来源期刊

Drug Delivery 医学-药学

CiteScore

11.80

自引率

5.00%

发文量

250

审稿时长

3.3 months

期刊介绍： Drug Delivery is an open access journal serving the academic and industrial communities with peer reviewed coverage of basic research, development, and application principles of drug delivery and targeting at molecular, cellular, and higher levels. Topics covered include all delivery systems including oral, pulmonary, nasal, parenteral and transdermal, and modes of entry such as controlled release systems; microcapsules, liposomes, vesicles, and macromolecular conjugates; antibody targeting; protein/peptide delivery; DNA, oligonucleotide and siRNA delivery. Papers on drug dosage forms and their optimization will not be considered unless they directly relate to the original drug delivery issues. Published articles present original research and critical reviews.

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