James Reigle, Oscar Lopez-Nunez, Erik Drysdale, Dua Abuquteish, Xiaoxuan Liu, Juan Putra, Lauren Erdman, Anne M. Griffiths, Surya Prasath, Iram Siddiqui, Jasbir Dhaliwal
{"title":"Using Deep Learning to Automate Eosinophil Counting in Pediatric Ulcerative Colitis Histopathological Images","authors":"James Reigle, Oscar Lopez-Nunez, Erik Drysdale, Dua Abuquteish, Xiaoxuan Liu, Juan Putra, Lauren Erdman, Anne M. Griffiths, Surya Prasath, Iram Siddiqui, Jasbir Dhaliwal","doi":"10.1101/2024.04.03.24305251","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> Accurate identification of inflammatory cells from mucosal histopathology images is important in diagnosing ulcerative colitis. The identification of eosinophils in the colonic mucosa has been associated with disease course. Cell counting is not only time-consuming but can also be subjective to human biases. In this study we developed an automatic eosinophilic cell counting tool from mucosal histopathology images, using deep learning.","PeriodicalId":501258,"journal":{"name":"medRxiv - Gastroenterology","volume":"282 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.04.03.24305251","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background Accurate identification of inflammatory cells from mucosal histopathology images is important in diagnosing ulcerative colitis. The identification of eosinophils in the colonic mucosa has been associated with disease course. Cell counting is not only time-consuming but can also be subjective to human biases. In this study we developed an automatic eosinophilic cell counting tool from mucosal histopathology images, using deep learning.