Osteochondroplastic tracheobronchopathy: Four case reports.

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-08 DOI:10.5867/medwave.2024.03.2792
Luis Alejandro Rodríguez Hidalgo, Natalia Carolina Cribillero Meza, Diana Cecilia Ruíz Caballero, L. C. Concepción Urteaga, Amalia Guadalupe Vega Fernández, Jorge Luis Cornejo Portella
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Abstract

Introduction Osteochondroplastic tracheobronchopathy is a rare benign chronic disease of unknown etiology. Bronchoscopy remains the gold standard for diagnosing osteochondroplastic tracheobronchopathy. Its typical findings are described as a cobblestone, rock garden, mountainscape, or stalactite cave appearance. The present work aims to show the main clinical features of this rare pathology. Clinical cases The clinical data of four middle-aged patients, three men and one woman, were analyzed. The main clinical symptoms were chronic cough, dyspnea, and dysphonia. The patient's preliminary diagnosis was made by computed axial tomography of the chest, confirmed by bronchoscopy and histopathological examination. Treatment included medication for symptoms and, in one case, cryosurgery and argon plasma coagulation. Discussion Diagnosing osteochondroplastic tracheobronchopathy was not easy, given its uncommon nature and non-specific symptoms often found in other pathologies. No case series articles on this pathology have been published in Peru. Therefore, we used the original articles published in other countries to reference our findings. Conclusion Osteochondroplastic tracheopathy is a benign disease that typically affects adults. Men are more likely to be affected. Its clinical manifestations are non-specific and frequently of pharyngeal origin, and the cause is not yet defined. Chest computed axial tomography combined with bronchoscopy are the main diagnostic procedures. There is no standard treatment with consistent therapeutic effects.
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骨软骨增生性气管支气管病:四份病例报告
导言骨软骨增生性气管支气管病是一种病因不明的罕见良性慢性疾病。支气管镜检查仍是诊断骨软骨增生性气管支气管病的金标准。其典型表现为鹅卵石、岩石花园、山景或钟乳石洞穴外观。临床病例分析了四名中年患者(三男一女)的临床资料。主要临床症状为慢性咳嗽、呼吸困难和发音障碍。患者的初步诊断是通过胸部计算机轴向断层扫描做出的,并经支气管镜检查和组织病理学检查证实。讨论由于骨软骨增生性气管支气管病并不常见,而且其非特异性症状在其他病症中也经常出现,因此诊断这种病症并不容易。秘鲁尚未发表过关于该病症的系列病例文章。结论骨软骨增生性气管病是一种良性疾病,通常发生在成年人身上。男性更易患病。该病的临床表现无特异性,常由咽部引起,病因尚未明确。胸部计算机轴向断层扫描和支气管镜检查是主要的诊断方法。目前尚无疗效一致的标准治疗方法。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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