{"title":"Nanoemulgel: An Innovative Carrier for Drug Delivery of Poorly\nWater-Soluble Drugs","authors":"Prevesh Kumar, Zaira Hussain, Phool Chandra, Diksha, Varsha Raj, Navneet Verma, Alok Singh","doi":"10.2174/0124681873286701240320111432","DOIUrl":null,"url":null,"abstract":"\n\nRecently, the delivery of hydrophobic/ poorly water-soluble drugs has been a difficult\ntask. Various approaches have been developed to counter the former and other main issues, such\nas solubility, bioavailability, etc. However, only a few formulations have successfully addressed\nthe problems and nanoemulgels are a standout among them. The nanoemulgel drug delivery approach\ncombines multiple benefits associated with emulsion and gel technologies to improve active\nmoiety solubility, bioavailability, and longevity. The article discusses the present status of nanoemulgel\nresearch and development, including its preparation methods and characterization techniques.\nAdditionally, the possible uses of nanoemulgel in targeted drug delivery and cosmetic/ personal\ncare products are discussed. Overall, nanoemulgel technology has shown significant\npromise as a novel approach to augment the transport of water-insoluble moieties. With further research\nas well as development, it is expected to have a substantial impact on the pharmaceutical\nand cosmetic industries. This inclusive review highlighted the role of nanoemulgels as a promising\ncarrier for drug delivery, with an overview of a few illustrations supporting the cause.\n","PeriodicalId":10818,"journal":{"name":"Current Nanomedicine","volume":"22 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Nanomedicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/0124681873286701240320111432","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Recently, the delivery of hydrophobic/ poorly water-soluble drugs has been a difficult
task. Various approaches have been developed to counter the former and other main issues, such
as solubility, bioavailability, etc. However, only a few formulations have successfully addressed
the problems and nanoemulgels are a standout among them. The nanoemulgel drug delivery approach
combines multiple benefits associated with emulsion and gel technologies to improve active
moiety solubility, bioavailability, and longevity. The article discusses the present status of nanoemulgel
research and development, including its preparation methods and characterization techniques.
Additionally, the possible uses of nanoemulgel in targeted drug delivery and cosmetic/ personal
care products are discussed. Overall, nanoemulgel technology has shown significant
promise as a novel approach to augment the transport of water-insoluble moieties. With further research
as well as development, it is expected to have a substantial impact on the pharmaceutical
and cosmetic industries. This inclusive review highlighted the role of nanoemulgels as a promising
carrier for drug delivery, with an overview of a few illustrations supporting the cause.