Risk Factors for Death of Burn Patients With Acute Respiratory Distress Syndrome.

Annals of burns and fire disasters Pub Date : 2023-12-31 eCollection Date: 2023-12-01
T D Hung, N N Lam
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Abstract

The aim of this study was to investigate factors independently affecting outcomes of post-burn ARDS patients at the time of ARDS onset. A prospective study was conducted on 66 patients with ARDS, treated in the ICU at the Le Huu Trac National Burns Hospital in Hanoi, Viet Nam, from 2014 to 2017. Patients were divided into a survivor and non-survivor group. Demographic criteria, burn severity, inhalation injury, clinical and subclinical features at ARDS onset were compared between the two groups. The results showed that overall mortality of ARDS patients was 62.12%. Logistic regression analysis indicated that at the time of ARDS onset, serum lactate level (OR=6.71), blood platelet count (OR=.99), static lung compliance (OR=.73) and driving pressure (OR=1.69) were independent risk factors for death, while patients' demographics, burn severity and ARDS severity did not significantly affect the mortality rate.

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急性呼吸窘迫综合征烧伤患者死亡的风险因素。
本研究旨在调查烧伤后 ARDS 患者在 ARDS 发病时独立影响预后的因素。这项前瞻性研究针对2014年至2017年在越南河内Le Huu Trac国家烧伤医院重症监护室接受治疗的66名ARDS患者。患者被分为幸存者组和非幸存者组。比较了两组患者的人口统计学标准、烧伤严重程度、吸入性损伤、ARDS发病时的临床和亚临床特征。结果显示,ARDS 患者的总死亡率为 62.12%。逻辑回归分析表明,ARDS发病时,血清乳酸水平(OR=6.71)、血小板计数(OR=.99)、静态肺顺应性(OR=.73)和驱动压力(OR=1.69)是死亡的独立危险因素,而患者的人口统计学特征、烧伤严重程度和ARDS严重程度对死亡率没有显著影响。
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