Delusions of love and passion in the behavioral variant of frontotemporal dementia.

IF 0.6 4区 医学 Q4 CLINICAL NEUROLOGY Neurocase Pub Date : 2023-04-01 Epub Date: 2024-04-27 DOI:10.1080/13554794.2024.2345110
Miguel Restrepo-Martínez, Jesus Ramirez-Bermudez, Isis So, Kristy Coleman, Elizabeth Finger
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Abstract

Erotomania (de Clérambault's syndrome) refers to the delusional belief that another person, usually socially unreachable, is in love with the holder of the delusion. The occurrence of erotomania in Frontotemporal Dementia has rarely been reported. We present the unique case of a 59-year-old woman with a strong family history of early-onset dementia in whom erotomania was the initial manifestation that led to a diagnosis of definite Behavioral Variant of Frontotemporal Dementia with a pathogenic missense mutation in the MAPT gene. Based on this case, we propose a hypothetical model for developing erotomania in patients with FTD.

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额颞叶痴呆症行为变异中的爱情和激情妄想。
情色妄想症(de Clérambault综合症)是指妄想他人(通常是社会上无法接触到的人)爱上了妄想者。额颞叶痴呆症患者出现艳情癖的报道很少。我们介绍了一例独特的病例,患者是一名 59 岁的女性,有强烈的早发性痴呆家族史,最初的表现是情欲妄想,最终被诊断为明确的行为变异型额颞叶痴呆症,其致病基因 MAPT 存在错义突变。根据这个病例,我们提出了一个FTD患者嗜睡症发病的假设模型。
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来源期刊
Neurocase
Neurocase 医学-精神病学
CiteScore
1.40
自引率
12.50%
发文量
70
审稿时长
6-12 weeks
期刊介绍: Neurocase is a rapid response journal of case studies and innovative group studies in neuropsychology, neuropsychiatry and behavioral neurology that speak to the neural basis of cognition. Four types of manuscript are considered for publication: single case investigations that bear directly on issues of relevance to theoretical issues or brain-behavior relationships; group studies of subjects with brain dysfunction that address issues relevant to the understanding of human cognition; reviews of important topics in the domains of neuropsychology, neuropsychiatry and behavioral neurology; and brief reports (up to 2500 words) that replicate previous reports dealing with issues of considerable significance. Of particular interest are investigations that include precise anatomical localization of lesions or neural activity via imaging or other techniques, as well as studies of patients with neurodegenerative diseases, since these diseases are becoming more common as our population ages. Topic reviews are included in most issues.
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